Cargando…

Interleukin 17A promotes gallbladder cancer invasiveness via ERK/NF-κB signal pathway mediated epithelial-to-mesenchymal transition

As a pro-inflammatory cytokine, Interleukin 17A (IL-17A) plays an important role in pathology of tumor microenvironment and inflammatory diseases. In this study, we intend to investigate the role of IL-17A on the metastasis of gallbladder cancer (GBC) and related mechanisms. The serum levels of IL-1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Kunlun, Tang, Hongwei, Zhu, Pengfei, Ye, Jianwen, Liu, Dong, Pu, Yansong, Zhang, Lei, Zhai, Wenlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255371/ https://www.ncbi.nlm.nih.gov/pubmed/32489459 http://dx.doi.org/10.7150/jca.40656

Ejemplares similares

Melatonin inhibits gallbladder cancer cell migration and invasion via ERK-mediated induction of epithelial-to-mesenchymal transition
por: Tang, Hongwei, et al.
Publicado: (2021)

Metformin suppresses hypoxia-induced migration via the HIF-1α/VEGF pathway in gallbladder cancer in vitro and in vivo
por: Ye, Jianwen, et al.
Publicado: (2019)

Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer
por: Ye, Jianwen, et al.
Publicado: (2021)

AREG mediates the epithelial-mesenchymal transition in pancreatic cancer cells via the EGFR/ERK/NF-κB signalling pathway
por: Wang, Li, et al.
Publicado: (2020)

SDC1 knockdown induces epithelial–mesenchymal transition and invasion of gallbladder cancer cells via the ERK/Snail pathway
por: Liu, Zixiang, et al.
Publicado: (2020)

Cigarette and IL-17A synergistically induce bronchial epithelial-mesenchymal transition via activating IL-17R/NF-κB signaling
por: Ma, Libing, et al.
Publicado: (2020)

NF-κB signaling in neoplastic transition from epithelial to mesenchymal phenotype
por: Oh, Amy, et al.
Publicado: (2023)

Melatonin inhibits proliferation, migration, and invasion by inducing ROS-mediated apoptosis via suppression of the PI3K/Akt/mTOR signaling pathway in gallbladder cancer cells
por: Chen, Kunlun, et al.
Publicado: (2021)

NF-κB–Dependent Snail Expression Promotes Epithelial–Mesenchymal Transition in Mastitis
por: Liu, Haokun, et al.
Publicado: (2021)

Disulfiram inhibits TGF-β-induced epithelial-mesenchymal transition and stem-like features in breast cancer via ERK/NF-κB/Snail pathway
por: Han, Dan, et al.
Publicado: (2015)

Korean Red Ginseng extract reduces hypoxia-induced epithelial-mesenchymal transition by repressing NF-κB and ERK1/2 pathways in colon cancer
por: Kim, Eui Joo, et al.
Publicado: (2018)

Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors
por: Adamopoulos, Iannis E, et al.
Publicado: (2010)

Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition
por: Zhang, Q, et al.
Publicado: (2016)

Interleukin-17 induces human alveolar epithelial to mesenchymal cell transition via the TGF-β1 mediated Smad2/3 and ERK1/2 activation
por: Wang, Ting, et al.
Publicado: (2017)

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-κB-dependent activation of Snail
por: Cichon, Magdalena A., et al.
Publicado: (2014)

Paxillin knockdown suppresses metastasis and epithelial-mesenchymal transition in colorectal cancer via the ERK signalling pathway
por: Wen, Long, et al.
Publicado: (2020)

ERK signalling modulates epigenome to drive epithelial to mesenchymal transition
por: Navandar, Mohit, et al.
Publicado: (2017)

Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT
por: Ye, Jianwen, et al.
Publicado: (2021)

Ubiquitin-specific peptidase 2 inhibits epithelial-mesenchymal transition in clear cell renal cell carcinoma metastasis by downregulating the NF-κB pathway
por: Duan, Jiachen, et al.
Publicado: (2022)

Monoacylglycerol lipase promotes progression of hepatocellular carcinoma via NF-κB-mediated epithelial-mesenchymal transition
por: Zhu, Weiping, et al.
Publicado: (2016)

Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation
por: Zhang, Rui, et al.
Publicado: (2020)

Submersion and hypoxia inhibit alveolar epithelial Na(+) transport through ERK/NF-κB signaling pathway
por: Zhou, Wei, et al.
Publicado: (2023)

Molecular Mechanisms of Epithelial to Mesenchymal Transition Regulated by ERK5 Signaling
por: Bhatt, Akshita B., et al.
Publicado: (2021)

KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition
por: Rao, Chaitra, et al.
Publicado: (2021)

Epithelial-to-mesenchymal transition in gallbladder cancer: from clinical evidence to cellular regulatory networks
por: Xu, Sunwang, et al.
Publicado: (2017)

Interleukin-8 drives epithelial-mesenchymal transition of human carcinomas
por: Fernando, Romaine I, et al.
Publicado: (2013)

RANKL Promotes Migration and Invasion of Hepatocellular Carcinoma Cells via NF-κB-Mediated Epithelial-Mesenchymal Transition
por: Song, Fang-Nan, et al.
Publicado: (2014)

Ezrin/NF-κB Pathway Regulates EGF-induced Epithelial-Mesenchymal Transition (EMT), Metastasis, and Progression of Osteosarcoma
por: Liu, Peng, et al.
Publicado: (2018)

Ursolic Acid Inhibits Epithelial-Mesenchymal Transition through the Axl/NF-κB Pathway in Gastric Cancer Cells
por: Li, Jinxia, et al.
Publicado: (2019)

RMP promotes epithelial-mesenchymal transition through NF-κB/CSN2/Snail pathway in hepatocellular carcinoma
por: Zhou, Wei, et al.
Publicado: (2017)

HLJ2 Effectively Ameliorates Colitis-Associated Cancer via Inhibition of NF-κB and Epithelial–Mesenchymal Transition
por: Song, Huachen, et al.
Publicado: (2020)

RUFY3 promotes the progression of hepatocellular carcinoma through activating NF-κB-mediated epithelial-mesenchymal transition
por: Zhang, Yang, et al.
Publicado: (2021)

Differential Role of ERK and p38 on NF-κB Activation in Helicobacter pylori-Infected Gastric Epithelial Cells
por: Seo, Ji Hye, et al.
Publicado: (2013)

Enterolactone modulates the ERK/NF-κB/Snail signaling pathway in triple-negative breast cancer cell line MDA-MB-231 to revert the TGF-β-induced epithelial–mesenchymal transition
por: Mali, Aniket V., et al.
Publicado: (2018)

EBV-miR-BART8-3p induces epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma cells through activating NF-κB and Erk1/2 pathways
por: Lin, Cheng, et al.
Publicado: (2018)

Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer
por: Bhatt, Akshita B., et al.
Publicado: (2021)

Periostin mediates epithelial-mesenchymal transition through the MAPK/ERK pathway in hepatoblastoma
por: Chen, Lu, et al.
Publicado: (2019)

MicroRNA-182 promotes epithelial-mesenchymal transition by targeting FOXN3 in gallbladder cancer
por: Zhang, Jianhong, et al.
Publicado: (2021)

Interleukin-6 induces epithelial-mesenchymal transition in human intrahepatic biliary epithelial cells
por: JIANG, GUI-XING, et al.
Publicado: (2016)

Oxymatrine inhibits the migration and invasion of hepatocellular carcinoma cells by reducing the activity of MMP-2/-9 via regulating p38 signaling pathway
por: Chen, Kunlun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_l7loar31hd9omrl6aml6hhfmp6