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Loss of PDK4 expression promotes proliferation, tumorigenicity, motility and invasion of hepatocellular carcinoma cells

Although the roles and underlying mechanisms of other PDK family members (i.e., PDK1, PDK2 and PDK3) in tumor progression have been extensively investigated and are well understood, the functions and underlying molecular mechanisms of pyruvate dehydrogenase kinase 4 (PDK4) in the tumorigenesis and p...

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Detalles Bibliográficos
Autores principales: Qin, Yu-Juan, Lin, Tao-Yan, Lin, Xiao-Lin, Liu, Yu, Zhao, Wen-Tao, Li, Xiao-Yan, Lian, Mei, Chen, Heng-Wei, Li, Yong-Long, Zhang, Xiao-Ling, Xiao, Dong, Jia, Jun-Shuang, Sun, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255379/
https://www.ncbi.nlm.nih.gov/pubmed/32489458
http://dx.doi.org/10.7150/jca.43459