Downregulation of c-FLIP and upregulation of DR-5 by cantharidin sensitizes TRAIL-mediated apoptosis in prostate cancer cells via autophagy flux

Tumor necrosis factor (TNF)-related apop-tosis-inducing ligand (TRAIL), a type II transmembrane protein, is a part of the TNF superfamily of cytokines. Cantharidin, a type of terpenoid, is extracted from the blister beetles (Mylabris genus) used in Traditional Chinese Medicine. Cantharidin elicits a...

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Detalles Bibliográficos
Autores principales: Nazim, Uddin Md, Yin, Honghua, Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255450/
https://www.ncbi.nlm.nih.gov/pubmed/32319535
http://dx.doi.org/10.3892/ijmm.2020.4566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255450/
https://www.ncbi.nlm.nih.gov/pubmed/32319535
http://dx.doi.org/10.3892/ijmm.2020.4566

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