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The JAK2/STAT3 pathway inhibitor, AG490, suppresses the abnormal behavior of keloid fibroblasts in vitro
AG490 is a selective inhibitor of the Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling pathway. The present study examined its effects on the abnormal behavior of human keloid fibroblasts (HKFs) and evaluated its potential use in the treatment of keloids. Hu...
Autores principales: | Zhou, Ying, Sun, Yuexin, Hou, Wenjun, Ma, Liwen, Tao, Yue, Li, Dan, Xu, Cui, Bao, Jun, Fan, Weixin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255460/ https://www.ncbi.nlm.nih.gov/pubmed/32377718 http://dx.doi.org/10.3892/ijmm.2020.4592 |
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