DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival

DNA replication protein Cdc45 is an integral part of the eukaryotic replicative helicase whose other components are the Mcm2-7 core, and GINS. We identified a PIP box motif in Leishmania donovani Cdc45. This motif is typically linked to interaction with the eukaryotic clamp proliferating cell nuclea...

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Detalles Bibliográficos
Autores principales: Yadav, Aarti, Sharma, Varshni, Pal, Jyoti, Gulati, Pallavi, Goel, Manisha, Chandra, Udita, Bansal, Neha, Saha, Swati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255605/
https://www.ncbi.nlm.nih.gov/pubmed/32413071
http://dx.doi.org/10.1371/journal.ppat.1008190

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