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Frailty Is Associated With Increased Hemagglutination-Inhibition Titers in a 4-Year Randomized Trial Comparing Standard- and High-Dose Influenza Vaccination

BACKGROUND: Although high-dose (HD) vaccines have been reported to stimulate higher antibody responses compared with standard-dose (SD) influenza vaccines, there have been limited studies on the impact of frailty on such responses. METHODS: We conducted a randomized, double-blind trial (2014/2015 to...

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Detalles Bibliográficos
Autores principales: Loeb, Nathalie, Andrew, Melissa K, Loeb, Mark, Kuchel, George A, Haynes, Laura, McElhaney, Janet E, Verschoor, Chris P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255647/
https://www.ncbi.nlm.nih.gov/pubmed/32500087
http://dx.doi.org/10.1093/ofid/ofaa148