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Novel specialized cell state and spatial compartments within the germinal center

Within germinal centers (GCs), complex and highly orchestrated molecular programs must balance proliferation, somatic hypermutation (SHM) and selection to both provide effective humoral immunity and to protect against genomic instability and neoplastic transformation. In contrast to this complexity,...

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Detalles Bibliográficos
Autores principales: Kennedy, Domenick E, Okoreeh, Michael K, Maienschein-Cline, Mark, Ai, Junting, Veselits, Margaret, McLean, Kaitlin C, Dhugana, Yogesh, Wang, Hong, Peng, Junmin, Chi, Hongbo, Mandal, Malay, Clark, Marcus R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255947/
https://www.ncbi.nlm.nih.gov/pubmed/32341509
http://dx.doi.org/10.1038/s41590-020-0660-2