Cargando…

Universal coronavirus vaccines: the time to start is now

The continued explosive spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) despite aggressive public health measures has triggered an unprecedented international vaccine effort. However, correlates of protection, which can help guide intelligent vaccine design, are not known for...

Descripción completa

Detalles Bibliográficos
Autores principales: Giurgea, Luca T., Han, Alison, Memoli, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256035/
https://www.ncbi.nlm.nih.gov/pubmed/32528732
http://dx.doi.org/10.1038/s41541-020-0198-1
_version_ 1783539833213288448
author Giurgea, Luca T.
Han, Alison
Memoli, Matthew J.
author_facet Giurgea, Luca T.
Han, Alison
Memoli, Matthew J.
author_sort Giurgea, Luca T.
collection PubMed
description The continued explosive spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) despite aggressive public health measures has triggered an unprecedented international vaccine effort. However, correlates of protection, which can help guide intelligent vaccine design, are not known for SARS-CoV-2. Research on influenza immunity and vaccine development may provide valuable lessons for coronavirus efforts, especially considering similarities in rapid evolutionary potential. The apparent inevitability of future novel coronavirus outbreaks must prompt work on a universal coronavirus vaccine.
format Online
Article
Text
id pubmed-7256035
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-72560352020-06-10 Universal coronavirus vaccines: the time to start is now Giurgea, Luca T. Han, Alison Memoli, Matthew J. NPJ Vaccines Comment The continued explosive spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) despite aggressive public health measures has triggered an unprecedented international vaccine effort. However, correlates of protection, which can help guide intelligent vaccine design, are not known for SARS-CoV-2. Research on influenza immunity and vaccine development may provide valuable lessons for coronavirus efforts, especially considering similarities in rapid evolutionary potential. The apparent inevitability of future novel coronavirus outbreaks must prompt work on a universal coronavirus vaccine. Nature Publishing Group UK 2020-05-28 /pmc/articles/PMC7256035/ /pubmed/32528732 http://dx.doi.org/10.1038/s41541-020-0198-1 Text en © This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2020 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Giurgea, Luca T.
Han, Alison
Memoli, Matthew J.
Universal coronavirus vaccines: the time to start is now
title Universal coronavirus vaccines: the time to start is now
title_full Universal coronavirus vaccines: the time to start is now
title_fullStr Universal coronavirus vaccines: the time to start is now
title_full_unstemmed Universal coronavirus vaccines: the time to start is now
title_short Universal coronavirus vaccines: the time to start is now
title_sort universal coronavirus vaccines: the time to start is now
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256035/
https://www.ncbi.nlm.nih.gov/pubmed/32528732
http://dx.doi.org/10.1038/s41541-020-0198-1
work_keys_str_mv AT giurgealucat universalcoronavirusvaccinesthetimetostartisnow
AT hanalison universalcoronavirusvaccinesthetimetostartisnow
AT memolimatthewj universalcoronavirusvaccinesthetimetostartisnow