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Copper-mediated thiol potentiation and mutagenesis-guided modeling suggest a highly conserved copper-binding motif in human OR2M3

Sulfur-containing compounds within a physiological relevant, natural odor space, such as the key food odorants, typically constitute the group of volatiles with the lowest odor thresholds. The observation that certain metals, such as copper, potentiate the smell of sulfur-containing, metal-coordinat...

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Detalles Bibliográficos
Autores principales: Haag, Franziska, Ahmed, Lucky, Reiss, Krystle, Block, Eric, Batista, Victor S., Krautwurst, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256108/
https://www.ncbi.nlm.nih.gov/pubmed/31435697
http://dx.doi.org/10.1007/s00018-019-03279-y