Enhanced NK-92 Cytotoxicity by CRISPR Genome Engineering Using Cas9 Ribonucleoproteins

Natural killer (NK) cells are an attractive cell-type for adoptive immunotherapy, but challenges in preparation of therapeutic primary NK cells restrict patient accessibility to NK cell immunotherapy. NK-92 is a well-characterized human NK cell line that has demonstrated promising anti-cancer activi...

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Detalles Bibliográficos
Autores principales: Huang, Rih-Sheng, Shih, Hsin-An, Lai, Min-Chi, Chang, Yao-Jen, Lin, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256201/
https://www.ncbi.nlm.nih.gov/pubmed/32528479
http://dx.doi.org/10.3389/fimmu.2020.01008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256201/
https://www.ncbi.nlm.nih.gov/pubmed/32528479
http://dx.doi.org/10.3389/fimmu.2020.01008

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