Preemptive Homology-Directed DNA Repair Fosters Complex Genomic Rearrangements in Hepatocellular Carcinoma

Degree of genomic instability closely correlates with poor prognosis, drug resistance as well as poor survival across human cancer of different origins. This study assessed the relationship between DNA damage response (DDR) and chromosome instability in hepatocellular carcinoma (HCC). We investigate...

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Detalles Bibliográficos
Autores principales: Sy, Shirley Ming-Hui, Guo, Yingying, Lan, Ying, Ng, Howin, Huen, Michael Shing-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256322/
https://www.ncbi.nlm.nih.gov/pubmed/32450552
http://dx.doi.org/10.1016/j.tranon.2020.100796

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