Pulmonary Silicosis Alters MicroRNA Expression in Rat Lung and miR-411-3p Exerts Anti-fibrotic Effects by Inhibiting MRTF-A/SRF Signaling

To identify potential therapeutic targets for pulmonary fibrosis induced by silica, we studied the effects of this disease on the expression of microRNAs (miRNAs) in the lung. Rattus norvegicus pulmonary silicosis models were used in conjunction with high-throughput screening of lung specimens to co...

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Detalles Bibliográficos
Autores principales: Gao, Xuemin, Xu, Dingjie, Li, Shumin, Wei, Zhongqiu, Li, Shifeng, Cai, Wenchen, Mao, Na, Jin, Fuyu, Li, Yaqian, Yi, Xue, Liu, Heliang, Xu, Hong, Yang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256439/
https://www.ncbi.nlm.nih.gov/pubmed/32464548
http://dx.doi.org/10.1016/j.omtn.2020.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256439/
https://www.ncbi.nlm.nih.gov/pubmed/32464548
http://dx.doi.org/10.1016/j.omtn.2020.05.005

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