Cargando…

CDK7 Mediates the Beta-Adrenergic Signaling in Thermogenic Brown and White Adipose Tissues

Cyclin-dependent kinases (CDKs) are emerging regulators of adipose tissue metabolism. Here we aimed to explore the role of CDK7 in thermogenic fat. We found that CDK7 brown adipose tissue (BAT)-specific knockout mice (Cdk7(bKO)) have decreased BAT mass and impaired β3-adrenergic signaling and develo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ji, Honglei, Chen, Yizhe, Castillo-Armengol, Judit, Dreos, René, Moret, Catherine, Niederhäuser, Guy, Delacuisine, Brigitte, Lopez-Mejia, Isabel C., Denechaud, Pierre-Damien, Fajas, Lluis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256631/ https://www.ncbi.nlm.nih.gov/pubmed/32464595 http://dx.doi.org/10.1016/j.isci.2020.101163

Ejemplares similares

CDK4 is an essential insulin effector in adipocytes
por: Lagarrigue, Sylviane, et al.
Publicado: (2022)

CDK4 is an essential insulin effector in adipocytes
por: Lagarrigue, Sylviane, et al.
Publicado: (2023)

Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues
por: Castillo‐Armengol, Judit, et al.
Publicado: (2020)

E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes
por: Giralt, Albert, et al.
Publicado: (2018)

Inter‐organ communication: a gatekeeper for metabolic health
por: Castillo‐Armengol, Judit, et al.
Publicado: (2019)

E2F1, a Novel Regulator of Metabolism
por: Denechaud, Pierre-Damien, et al.
Publicado: (2017)

Chromatin immunoprecipitation improvements for the processing of small frozen pieces of adipose tissue
por: Castellano-Castillo, Daniel, et al.
Publicado: (2018)

Brown Adipose Tissue Thermogenic Capacity Is Regulated by Elovl6
por: Tan, Chong Yew, et al.
Publicado: (2015)

Mfn2 is critical for brown adipose tissue thermogenic function
por: Boutant, Marie, et al.
Publicado: (2017)

Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivo
por: Markan, Kathleen R., et al.
Publicado: (2020)

Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR
por: Castellano-Castillo, Daniel, et al.
Publicado: (2019)

Histone Deacetylase 3 Prepares Brown Adipose Tissue For Acute Thermogenic Challenge
por: Emmett, Matthew J., et al.
Publicado: (2017)

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
por: Bartelt, Alexander, et al.
Publicado: (2018)

Gastric Bypass Sensitizes Sympathetic and Thermogenic Activity of Brown Adipose Tissue to Cold Exposure
por: Chu, Yi, et al.
Publicado: (2021)

Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue
por: Samms, Ricardo J., et al.
Publicado: (2022)

Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning
por: Shi, Fubiao, et al.
Publicado: (2023)

Myoglobin‐mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humans
por: Christen, Lisa, et al.
Publicado: (2022)

Shades of Brown: A Model for Thermogenic Fat
por: Dempersmier, Jon, et al.
Publicado: (2015)

Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing
por: Gonzalez-Hurtado, Elsie, et al.
Publicado: (2017)

Brown Adipose Tissue, Diet-Induced Thermogenesis, and Thermogenic Food Ingredients: From Mice to Men
por: Saito, Masayuki, et al.
Publicado: (2020)

White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment
por: Rabiee, Atefeh, et al.
Publicado: (2020)

Treatment with atrial natriuretic peptide induces adipose tissue browning and exerts thermogenic actions in vivo
por: Kimura, Haruka, et al.
Publicado: (2021)

RNA-Seq reveals miRNA role in thermogenic regulation in brown adipose tissues of goats
por: Liu, Xin, et al.
Publicado: (2022)

Thermogenic recruitment of brown and brite/beige adipose tissues is not obligatorily associated with macrophage accretion or attrition
por: Boulet, Nathalie, et al.
Publicado: (2021)

Progress and obstacles in transplantation of brown adipose tissue or engineered cells with thermogenic potential for metabolic benefits
por: Zhu, Tao, et al.
Publicado: (2023)

Isoenergetic Feeding of Low Carbohydrate-High Fat Diets Does Not Increase Brown Adipose Tissue Thermogenic Capacity in Rats
por: Betz, Matthias J., et al.
Publicado: (2012)

CDK4, a new metabolic sensor that antagonizes AMPK
por: Fajas, L., et al.
Publicado: (2018)

Cdkn2a deficiency promotes adipose tissue browning
por: Rabhi, Nabil, et al.
Publicado: (2017)

Regulation of brown adipose tissue recruitment, metabolism and thermogenic function by peroxisome proliferator-activated receptor γ
por: Bolsoni-Lopes, Andressa, et al.
Publicado: (2015)

Berardinelli–Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing
por: Zhou, Hongyi, et al.
Publicado: (2020)

Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice
por: Park, Anna, et al.
Publicado: (2023)

Corrigendum to “Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivo” [Molecular Metabolism 36 (2020) 100965]
por: Markan, Kathleen R., et al.
Publicado: (2020)

CDK4, pRB and E2F1: connected to insulin
por: Fajas, Lluis, et al.
Publicado: (2010)

Maternal high-fat diet during lactation impairs thermogenic function of brown adipose tissue in offspring mice
por: Liang, Xingwei, et al.
Publicado: (2016)

Alpha-Linolenic Acid-Enriched Butter Promotes Fatty Acid Remodeling and Thermogenic Activation in the Brown Adipose Tissue
por: You, Mikyoung, et al.
Publicado: (2020)

Effects of aging-induced obesity on the transcriptional expression of adipogenesis and thermogenic activity in the gonadal white adipose, brown adipose, and skeletal muscle tissues
por: Kwon, Insu, et al.
Publicado: (2023)

Brown and Beige Fat: Molecular Parts of a Thermogenic Machine
por: Cohen, Paul, et al.
Publicado: (2015)

An OLTAM system for analysis of brown/beige fat thermogenic activity
por: Kim, Dong-il, et al.
Publicado: (2018)

MicroRNA Regulation of Brown Adipogenesis and Thermogenic Energy Expenditure
por: Shamsi, Farnaz, et al.
Publicado: (2017)

3-Iodothyronamine Affects Thermogenic Substrates’ Mobilization in Brown Adipocytes
por: Gencarelli, Manuela, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fuudi4ccs2r946n1l21fm4tm2m