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Delta-Globin Gene Expression Is Enhanced in vivo by Interferon Type I

Beta hemoglobinopathies are widely spread monogenic lethal diseases. Delta-globin gene activation has been proposed as a possible approach for curing these pathologies. The therapeutic potential of delta-globin, the non-alpha component of Hemoglobin A(2) (α2δ2; HbA2), has been demonstrated in a mous...

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Detalles Bibliográficos
Autores principales:	Manchinu, Maria Francesca, Simbula, Michela, Caria, Cristian Antonio, Musu, Ester, Perseu, Lucia, Porcu, Susanna, Steri, Maristella, Poddie, Daniela, Frau, Jessica, Cocco, Eleonora, Manunza, Laura, Barella, Susanna, Ristaldi, Maria Serafina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256663/ https://www.ncbi.nlm.nih.gov/pubmed/32528964 http://dx.doi.org/10.3389/fmed.2020.00163

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