Cargando…

IL-38 restrains inflammatory response of collagen-induced arthritis in rats via SIRT1/HIF-1α signaling pathway

Objective: To observe the restraining effect of IL-38 on inflammatory response in collagen-induced arthritis rats (CIA), and to explore the regulatory mechanism of SIRT1/HIF-1α signaling pathway. Methods: 40 SD rats were randomly divided into Control group, CIA group, CLL group and CLH group, with 1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pei, Bing, Chen, Keyan, Zhou, Shenglai, Min, Dongyu, Xiao, Weiguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Immunology & Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256678/ https://www.ncbi.nlm.nih.gov/pubmed/32347300 http://dx.doi.org/10.1042/BSR20182431

Ejemplares similares

HIF1α is required for NK cell metabolic adaptation during virus infection
por: Victorino, Francisco, et al.
Publicado: (2021)

Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice
por: Ryu, Seungjin, et al.
Publicado: (2021)

Icariin inhibits the inflammation through down-regulating NF-κB/HIF-2α signal pathways in chondrocytes
por: Wang, Pengzhen, et al.
Publicado: (2020)

c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells
por: Tizian, Caroline, et al.
Publicado: (2020)

Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis: Impact of Inflammation and Antirheumatic Treatment
por: Kerola, Anne Mirjam, et al.
Publicado: (2021)

Correction: c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells
por: Tizian, Caroline, et al.
Publicado: (2020)

Effect of Eriodictyol on Collagen-Induced Arthritis in Rats by Akt/HIF-1α Pathway
por: Lei, ZhongHua, et al.
Publicado: (2020)

Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells
por: Kim, Dong Hyun, et al.
Publicado: (2021)

Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion
por: Smith, Katherine A, et al.
Publicado: (2018)

Pathogen infection and cholesterol deficiency activate the C. elegans p38 immune pathway through a TIR-1/SARM1 phase transition
por: Peterson, Nicholas D, et al.
Publicado: (2022)

Coix seed oil alleviates synovial angiogenesis through suppressing HIF-1α/VEGF-A signaling pathways via SIRT1 in collagen-induced arthritis rats
por: Xu, Qiangqiang, et al.
Publicado: (2023)

The recombinant anti-TNF-α fusion protein ameliorates rheumatoid arthritis by the protective role of autophagy
por: Chen, Xiaole, et al.
Publicado: (2020)

BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages
por: Li, Jie, et al.
Publicado: (2020)

Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2
por: Tsyklauri, Oksana, et al.
Publicado: (2023)

HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4(+)CD8(+) thymocytes for CD4-lineage commitment
por: Philips, Rachael Laura, et al.
Publicado: (2019)

Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation
por: Queiroz, Rayner M. L., et al.
Publicado: (2022)

SIRT1 attenuates renal fibrosis by repressing HIF-2α
por: Li, Peipei, et al.
Publicado: (2021)

Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome
por: Marié, Isabelle J, et al.
Publicado: (2021)

Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α
por: Tezera, Liku B, et al.
Publicado: (2020)

HIF-1α regulates IL-1β and IL-17 in sarcoidosis
por: Talreja, Jaya, et al.
Publicado: (2019)

Iguratimod Restrains Circulating Follicular Helper T Cell Function by Inhibiting Glucose Metabolism via Hif1α-HK2 Axis in Rheumatoid Arthritis
por: Bai, Ziran, et al.
Publicado: (2022)

IL-33 induces granzyme C expression in murine mast cells via an MSK1/2-CREB-dependent pathway
por: Phair, Iain R., et al.
Publicado: (2022)

Inhibitory IL-10-producing CD4(+) T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1
por: Clement, Mathew, et al.
Publicado: (2023)

Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects
por: de Graaf, Dennis M., et al.
Publicado: (2020)

Blood flow guides sequential support of neutrophil arrest and diapedesis by PILR-β1 and PILR-α
por: Li, Yu-Tung, et al.
Publicado: (2019)

Neonatal-derived IL-17 producing dermal γδ T cells are required to prevent spontaneous atopic dermatitis
por: Spidale, Nicholas A, et al.
Publicado: (2020)

Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches
por: Asahi, Takuma, et al.
Publicado: (2023)

Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses
por: Lundahl, Mimmi LE, et al.
Publicado: (2022)

Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon
por: Peñin-Franch, Alejandro, et al.
Publicado: (2022)

IL‐38 prevents induction of trained immunity by inhibition of mTOR signaling
por: de Graaf, Dennis M., et al.
Publicado: (2021)

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α
por: Simões-Sousa, Susana, et al.
Publicado: (2018)

Structure of the IL-27 quaternary receptor signaling complex
por: Caveney, Nathanael A, et al.
Publicado: (2022)

IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25(+)Foxp3(-) T cells
por: Tomala, Jakub, et al.
Publicado: (2021)

Opposite effects of HIF-1α and HIF-2α on the regulation of IL-8 expression in endothelial cells
por: Florczyk, Urszula, et al.
Publicado: (2011)

Neem Leaf Glycoprotein Restrains VEGF Production by Direct Modulation of HIF1α-Linked Upstream and Downstream Cascades
por: Saha, Akata, et al.
Publicado: (2020)

IL18 signaling promotes homing of mature Tregs into the thymus
por: Peligero-Cruz, Cristina, et al.
Publicado: (2020)

Hyperbaric oxygen in animal model of rheumatoid arthritis: Analysis Of HIF-1α, ACPA and IL-17a
por: Harnanik, Titut, et al.
Publicado: (2020)

B cell receptor-induced IL-10 production from neonatal mouse CD19(+)CD43(-) cells depends on STAT5-mediated IL-6 secretion
por: Sakai, Jiro, et al.
Publicado: (2023)

Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis
por: Weinstock, Ada, et al.
Publicado: (2021)

IL‐31 transgenic mice show reduced allergen‐induced lung inflammation
por: Neuper, Theresa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fsk43cq75168v6okh05q03vd5n