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Familial Mediterranean Fever Complicated by a Triad of Adrenal Crisis: Amyloid Goiter and Cardiac Amyloidosis

BACKGROUND: FMF is a common disease in the Mediterranean populations and may be complicated by AA amyloidosis. The coexistence of adrenal and thyroid amyloidosis in AA amyloidosis secondary to familial Mediterranean fever (FMF) is an extremely rare reported condition. We presented a previously unrep...

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Autores principales: Abukhalaf, Sadi A., Dandis, Beesan W., Za'tari, Tasnim, Amro, Adham M., Alzughayyar, Tareq Z., Rajabi, Yazan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256690/
https://www.ncbi.nlm.nih.gov/pubmed/32518703
http://dx.doi.org/10.1155/2020/7865291
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author Abukhalaf, Sadi A.
Dandis, Beesan W.
Za'tari, Tasnim
Amro, Adham M.
Alzughayyar, Tareq Z.
Rajabi, Yazan A.
author_facet Abukhalaf, Sadi A.
Dandis, Beesan W.
Za'tari, Tasnim
Amro, Adham M.
Alzughayyar, Tareq Z.
Rajabi, Yazan A.
author_sort Abukhalaf, Sadi A.
collection PubMed
description BACKGROUND: FMF is a common disease in the Mediterranean populations and may be complicated by AA amyloidosis. The coexistence of adrenal and thyroid amyloidosis in AA amyloidosis secondary to familial Mediterranean fever (FMF) is an extremely rare reported condition. We presented a previously unreported triad of adrenal, thyroid, and cardiac amyloidosis secondary to FMF. Presentation of Case. We reported a 23-year-old Palestinian male patient presented with hypotension, vomiting, diarrhea, and abdominal pain. The patient was subsequently diagnosed to have an adrenal crisis with both amyloid goiter and cardiac amyloidosis. CONCLUSION: It is crucial to recognize the adrenal crisis in patients with AA amyloidosis secondary to FMF who present similarly to acute FMF inflammatory episodes. The adrenal crisis has high morbidity and mortality, especially if not recognized early in the course of the disease.
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spelling pubmed-72566902020-06-08 Familial Mediterranean Fever Complicated by a Triad of Adrenal Crisis: Amyloid Goiter and Cardiac Amyloidosis Abukhalaf, Sadi A. Dandis, Beesan W. Za'tari, Tasnim Amro, Adham M. Alzughayyar, Tareq Z. Rajabi, Yazan A. Case Rep Rheumatol Case Report BACKGROUND: FMF is a common disease in the Mediterranean populations and may be complicated by AA amyloidosis. The coexistence of adrenal and thyroid amyloidosis in AA amyloidosis secondary to familial Mediterranean fever (FMF) is an extremely rare reported condition. We presented a previously unreported triad of adrenal, thyroid, and cardiac amyloidosis secondary to FMF. Presentation of Case. We reported a 23-year-old Palestinian male patient presented with hypotension, vomiting, diarrhea, and abdominal pain. The patient was subsequently diagnosed to have an adrenal crisis with both amyloid goiter and cardiac amyloidosis. CONCLUSION: It is crucial to recognize the adrenal crisis in patients with AA amyloidosis secondary to FMF who present similarly to acute FMF inflammatory episodes. The adrenal crisis has high morbidity and mortality, especially if not recognized early in the course of the disease. Hindawi 2020-05-19 /pmc/articles/PMC7256690/ /pubmed/32518703 http://dx.doi.org/10.1155/2020/7865291 Text en Copyright © 2020 Sadi A. Abukhalaf et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Abukhalaf, Sadi A.
Dandis, Beesan W.
Za'tari, Tasnim
Amro, Adham M.
Alzughayyar, Tareq Z.
Rajabi, Yazan A.
Familial Mediterranean Fever Complicated by a Triad of Adrenal Crisis: Amyloid Goiter and Cardiac Amyloidosis
title Familial Mediterranean Fever Complicated by a Triad of Adrenal Crisis: Amyloid Goiter and Cardiac Amyloidosis
title_full Familial Mediterranean Fever Complicated by a Triad of Adrenal Crisis: Amyloid Goiter and Cardiac Amyloidosis
title_fullStr Familial Mediterranean Fever Complicated by a Triad of Adrenal Crisis: Amyloid Goiter and Cardiac Amyloidosis
title_full_unstemmed Familial Mediterranean Fever Complicated by a Triad of Adrenal Crisis: Amyloid Goiter and Cardiac Amyloidosis
title_short Familial Mediterranean Fever Complicated by a Triad of Adrenal Crisis: Amyloid Goiter and Cardiac Amyloidosis
title_sort familial mediterranean fever complicated by a triad of adrenal crisis: amyloid goiter and cardiac amyloidosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256690/
https://www.ncbi.nlm.nih.gov/pubmed/32518703
http://dx.doi.org/10.1155/2020/7865291
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