New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B

The subject of the study was phenotypic marking of the antibiotic susceptibility and MLS(B) resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), l...

Descripción completa

Detalles Bibliográficos
Autores principales: SZEMRAJ, MAGDALENA, KWASZEWSKA, ANNA, SZEWCZYK, ELIGIA M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Exeley Inc. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256696/
https://www.ncbi.nlm.nih.gov/pubmed/30015464
http://dx.doi.org/10.21307/pjm-2018-028
_version_ 1783539968332791808
author SZEMRAJ, MAGDALENA
KWASZEWSKA, ANNA
SZEWCZYK, ELIGIA M.
author_facet SZEMRAJ, MAGDALENA
KWASZEWSKA, ANNA
SZEWCZYK, ELIGIA M.
author_sort SZEMRAJ, MAGDALENA
collection PubMed
description The subject of the study was phenotypic marking of the antibiotic susceptibility and MLS(B) resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), lnu(A), msr(A), msr(B) and mph(C) genes. Clinical isolates showed wide resistance to antibiotics. In 89% clinical isolates and 72% skin microbiota a constitutive type of MLS(B) resistance was found. In 12 clinical isolates the erm(C) gene was detected-eight of which had erm(X) as well as erm(C), two harboured erm(X), erm(C) and erm(A) and two demonstrated only erm(C).
format Online
Article
Text
id pubmed-7256696
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Exeley Inc.
record_format MEDLINE/PubMed
spelling pubmed-72566962020-06-03 New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B SZEMRAJ, MAGDALENA KWASZEWSKA, ANNA SZEWCZYK, ELIGIA M. Pol J Microbiol Microbiology The subject of the study was phenotypic marking of the antibiotic susceptibility and MLS(B) resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), lnu(A), msr(A), msr(B) and mph(C) genes. Clinical isolates showed wide resistance to antibiotics. In 89% clinical isolates and 72% skin microbiota a constitutive type of MLS(B) resistance was found. In 12 clinical isolates the erm(C) gene was detected-eight of which had erm(X) as well as erm(C), two harboured erm(X), erm(C) and erm(A) and two demonstrated only erm(C). Exeley Inc. 2018-06 2018-06-30 /pmc/articles/PMC7256696/ /pubmed/30015464 http://dx.doi.org/10.21307/pjm-2018-028 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Microbiology
SZEMRAJ, MAGDALENA
KWASZEWSKA, ANNA
SZEWCZYK, ELIGIA M.
New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_full New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_fullStr New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_full_unstemmed New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_short New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_sort new gene responsible for resistance of clinical corynebacteria to macrolide, lincosamide and streptogramin b
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256696/
https://www.ncbi.nlm.nih.gov/pubmed/30015464
http://dx.doi.org/10.21307/pjm-2018-028
work_keys_str_mv AT szemrajmagdalena newgeneresponsibleforresistanceofclinicalcorynebacteriatomacrolidelincosamideandstreptograminb
AT kwaszewskaanna newgeneresponsibleforresistanceofclinicalcorynebacteriatomacrolidelincosamideandstreptograminb
AT szewczykeligiam newgeneresponsibleforresistanceofclinicalcorynebacteriatomacrolidelincosamideandstreptograminb

Ejemplares similares