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An Epoxide Intermediate in Glycosidase Catalysis
[Image: see text] Retaining glycoside hydrolases cleave their substrates through stereochemical retention at the anomeric position. Typically, this involves two-step mechanisms using either an enzymatic nucleophile via a covalent glycosyl enzyme intermediate or neighboring-group participation by a s...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256955/ https://www.ncbi.nlm.nih.gov/pubmed/32490192 http://dx.doi.org/10.1021/acscentsci.0c00111 |