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ESHRE PGT Consortium good practice recommendations for the organisation of PGT

The field of preimplantation genetic testing (PGT) is evolving fast, and best practice advice is essential for regulation and standardisation of diagnostic testing. The previous ESHRE guidelines on best practice for preimplantation genetic diagnosis, published in 2005 and 2011, are considered outdat...

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Autores principales: Carvalho, Filipa, Coonen, Edith, Goossens, Veerle, Kokkali, Georgia, Rubio, Carmen, Meijer-Hoogeveen, Madelon, Moutou, Céline, Vermeulen, Nathalie, De Rycke, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257038/
https://www.ncbi.nlm.nih.gov/pubmed/32524036
http://dx.doi.org/10.1093/hropen/hoaa021
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author Carvalho, Filipa
Coonen, Edith
Goossens, Veerle
Kokkali, Georgia
Rubio, Carmen
Meijer-Hoogeveen, Madelon
Moutou, Céline
Vermeulen, Nathalie
De Rycke, Martine
author_facet Carvalho, Filipa
Coonen, Edith
Goossens, Veerle
Kokkali, Georgia
Rubio, Carmen
Meijer-Hoogeveen, Madelon
Moutou, Céline
Vermeulen, Nathalie
De Rycke, Martine
collection PubMed
description The field of preimplantation genetic testing (PGT) is evolving fast, and best practice advice is essential for regulation and standardisation of diagnostic testing. The previous ESHRE guidelines on best practice for preimplantation genetic diagnosis, published in 2005 and 2011, are considered outdated and the development of new papers outlining recommendations for good practice in PGT was necessary. The current updated version of the recommendations for good practice is, similar to the 2011 version, split into four documents, one of which covers the organisation of a PGT centre. The other documents focus on the different technical aspects of embryo biopsy, PGT for monogenic/single-gene defects (PGT-M) and PGT for chromosomal structural rearrangements/aneuploidies (PGT-SR/PGT-A). The current document outlines the steps prior to starting a PGT cycle, with details on patient inclusion and exclusion, and counselling and information provision. Also, recommendations are provided on the follow-up of PGT pregnancies and babies. Finally, some further recommendations are made on the practical organisation of an IVF/PGT centre, including basic requirements, transport PGT and quality management. This document, together with the documents on embryo biopsy, PGT-M and PGT-SR/PGT-A, should assist everyone interested in PGT in developing the best laboratory and clinical practice possible.
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spelling pubmed-72570382020-06-09 ESHRE PGT Consortium good practice recommendations for the organisation of PGT Carvalho, Filipa Coonen, Edith Goossens, Veerle Kokkali, Georgia Rubio, Carmen Meijer-Hoogeveen, Madelon Moutou, Céline Vermeulen, Nathalie De Rycke, Martine Hum Reprod Open ESHRE Pages The field of preimplantation genetic testing (PGT) is evolving fast, and best practice advice is essential for regulation and standardisation of diagnostic testing. The previous ESHRE guidelines on best practice for preimplantation genetic diagnosis, published in 2005 and 2011, are considered outdated and the development of new papers outlining recommendations for good practice in PGT was necessary. The current updated version of the recommendations for good practice is, similar to the 2011 version, split into four documents, one of which covers the organisation of a PGT centre. The other documents focus on the different technical aspects of embryo biopsy, PGT for monogenic/single-gene defects (PGT-M) and PGT for chromosomal structural rearrangements/aneuploidies (PGT-SR/PGT-A). The current document outlines the steps prior to starting a PGT cycle, with details on patient inclusion and exclusion, and counselling and information provision. Also, recommendations are provided on the follow-up of PGT pregnancies and babies. Finally, some further recommendations are made on the practical organisation of an IVF/PGT centre, including basic requirements, transport PGT and quality management. This document, together with the documents on embryo biopsy, PGT-M and PGT-SR/PGT-A, should assist everyone interested in PGT in developing the best laboratory and clinical practice possible. Oxford University Press 2020-05-29 /pmc/articles/PMC7257038/ /pubmed/32524036 http://dx.doi.org/10.1093/hropen/hoaa021 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle ESHRE Pages
Carvalho, Filipa
Coonen, Edith
Goossens, Veerle
Kokkali, Georgia
Rubio, Carmen
Meijer-Hoogeveen, Madelon
Moutou, Céline
Vermeulen, Nathalie
De Rycke, Martine
ESHRE PGT Consortium good practice recommendations for the organisation of PGT
title ESHRE PGT Consortium good practice recommendations for the organisation of PGT
title_full ESHRE PGT Consortium good practice recommendations for the organisation of PGT
title_fullStr ESHRE PGT Consortium good practice recommendations for the organisation of PGT
title_full_unstemmed ESHRE PGT Consortium good practice recommendations for the organisation of PGT
title_short ESHRE PGT Consortium good practice recommendations for the organisation of PGT
title_sort eshre pgt consortium good practice recommendations for the organisation of pgt
topic ESHRE Pages
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257038/
https://www.ncbi.nlm.nih.gov/pubmed/32524036
http://dx.doi.org/10.1093/hropen/hoaa021
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