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HBV X protein-based therapeutic vaccine accelerates viral antigen clearance by mobilizing monocyte infiltration into the liver in HBV carrier mice
BACKGROUND: Hepatitis B virus (HBV) persistently infected about 250 million people worldwide, and a curative treatment remains an unmet medical need. Among many approaches to treat chronic hepatitis B (CHB), therapeutic vaccines have been developed for two decades, but none have yielded promising re...
Autores principales: | Horng, Jau-Hau, Lin, Wei-Hsiang, Wu, Chang-Ru, Lin, You-Yu, Wu, Li-Ling, Chen, Ding-Shinn, Chen, Pei-Jer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257178/ https://www.ncbi.nlm.nih.gov/pubmed/32466788 http://dx.doi.org/10.1186/s12929-020-00662-x |
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