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Complement activating ABO anti-A IgM/IgG act synergistically to cause erythrophagocytosis: implications among minor ABO incompatible transfusions

BACKGROUND: Typically minor ABO incompatible platelet products are transfused without any incident, yet serious hemolytic transfusion reactions occur. To mitigate these events, ABO ‘low titer’ products are used for minor ABO incompatible transfusions. We sought to understand the role of IgM/IgG and...

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Detalles Bibliográficos
Autores principales:	Pandey, Priyanka, Anani, Waseem Q., Pugh, Tina, Gottschall, Jerome L., Denomme, Gregory A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257204/ https://www.ncbi.nlm.nih.gov/pubmed/32466782 http://dx.doi.org/10.1186/s12967-020-02378-w

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