Asiaticoside inhibits TGF-β1-induced mesothelial-mesenchymal transition and oxidative stress via the Nrf2/HO-1 signaling pathway in the human peritoneal mesothelial cell line HMrSV5

BACKGROUND: Peritoneal fibrosis (PF) is a frequent complication caused by peritoneal dialysis (PD). Peritoneal mesothelial cells (PMCs), the first barrier of the peritoneum, play an important role in maintaining structure and function in the peritoneum during PD. Mesothelial-mesenchymal transition (...

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Detalles Bibliográficos
Autores principales: Zhao, Junyi, Shi, Jun, Shan, Yun, Yu, Manshu, Zhu, Xiaolin, Zhu, Yilin, Liu, Li, Sheng, Meixiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257216/
https://www.ncbi.nlm.nih.gov/pubmed/32514269
http://dx.doi.org/10.1186/s11658-020-00226-9

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