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The COVID-19 infection: lessons from the Italian experience

The first case of the new coronavirus, COVID-19, was reported in China on 17 November 2019. By the end of March 2020, the rapid global spread of infection affected over 1 million people. Italy is one of the countries most impacted, with over 100,000 positive cases identified. The first detected case...

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Autores principales: Romagnani, Paola, Gnone, Guido, Guzzi, Francesco, Negrini, Simone, Guastalla, Andrea, Annunziato, Francesco, Romagnani, Sergio, De Palma, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Palgrave Macmillan UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257358/
https://www.ncbi.nlm.nih.gov/pubmed/32472024
http://dx.doi.org/10.1057/s41271-020-00229-y
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author Romagnani, Paola
Gnone, Guido
Guzzi, Francesco
Negrini, Simone
Guastalla, Andrea
Annunziato, Francesco
Romagnani, Sergio
De Palma, Raffaele
author_facet Romagnani, Paola
Gnone, Guido
Guzzi, Francesco
Negrini, Simone
Guastalla, Andrea
Annunziato, Francesco
Romagnani, Sergio
De Palma, Raffaele
author_sort Romagnani, Paola
collection PubMed
description The first case of the new coronavirus, COVID-19, was reported in China on 17 November 2019. By the end of March 2020, the rapid global spread of infection affected over 1 million people. Italy is one of the countries most impacted, with over 100,000 positive cases identified. The first detected cases were reported on 21 February 2020 in two Italian towns: Vo’ Euganeo in the Province of Padua, Veneto region, and Codogno, in the Province of Lodi, Lombardy. In the next weeks the epidemic spread quickly across the country but mainly in the north of Italy. The two regions: Veneto and Lombardy, implemented different strategies to control the viral spread. In Veneto, health personnel tested both symptomatic and asymptomatic subjects, while in Lombardy only symptomatic cases were investigated. We analyzed the evolution of the epidemic in these regions and showed that testing both symptomatic and asymptomatic cases is a more effective strategy to mitigate the epidemic impact. We strongly recommend that decision-makers: ensure early isolation of symptomatic patients and rapid identification of their contacts; maximize testing rapidly, especially among people with multiple daily contacts with infected populations, high exposure to the public in essential services; rapidly increase diagnostic capacity by mobilizing trained personnel capable of performing rRT-PCR on respiratory samples; equip the population with protective masks.
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spelling pubmed-72573582020-05-29 The COVID-19 infection: lessons from the Italian experience Romagnani, Paola Gnone, Guido Guzzi, Francesco Negrini, Simone Guastalla, Andrea Annunziato, Francesco Romagnani, Sergio De Palma, Raffaele J Public Health Policy Viewpoint The first case of the new coronavirus, COVID-19, was reported in China on 17 November 2019. By the end of March 2020, the rapid global spread of infection affected over 1 million people. Italy is one of the countries most impacted, with over 100,000 positive cases identified. The first detected cases were reported on 21 February 2020 in two Italian towns: Vo’ Euganeo in the Province of Padua, Veneto region, and Codogno, in the Province of Lodi, Lombardy. In the next weeks the epidemic spread quickly across the country but mainly in the north of Italy. The two regions: Veneto and Lombardy, implemented different strategies to control the viral spread. In Veneto, health personnel tested both symptomatic and asymptomatic subjects, while in Lombardy only symptomatic cases were investigated. We analyzed the evolution of the epidemic in these regions and showed that testing both symptomatic and asymptomatic cases is a more effective strategy to mitigate the epidemic impact. We strongly recommend that decision-makers: ensure early isolation of symptomatic patients and rapid identification of their contacts; maximize testing rapidly, especially among people with multiple daily contacts with infected populations, high exposure to the public in essential services; rapidly increase diagnostic capacity by mobilizing trained personnel capable of performing rRT-PCR on respiratory samples; equip the population with protective masks. Palgrave Macmillan UK 2020-05-29 2020 /pmc/articles/PMC7257358/ /pubmed/32472024 http://dx.doi.org/10.1057/s41271-020-00229-y Text en © Springer Nature Limited 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Viewpoint
Romagnani, Paola
Gnone, Guido
Guzzi, Francesco
Negrini, Simone
Guastalla, Andrea
Annunziato, Francesco
Romagnani, Sergio
De Palma, Raffaele
The COVID-19 infection: lessons from the Italian experience
title The COVID-19 infection: lessons from the Italian experience
title_full The COVID-19 infection: lessons from the Italian experience
title_fullStr The COVID-19 infection: lessons from the Italian experience
title_full_unstemmed The COVID-19 infection: lessons from the Italian experience
title_short The COVID-19 infection: lessons from the Italian experience
title_sort covid-19 infection: lessons from the italian experience
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257358/
https://www.ncbi.nlm.nih.gov/pubmed/32472024
http://dx.doi.org/10.1057/s41271-020-00229-y
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