Angiotensin-Converting Enzyme Inhibitor Protects Against Cisplatin Nephrotoxicity by Modulating Kinin B1 Receptor Expression and Aminopeptidase P Activity in Mice

Cisplatin is a highly effective chemotherapeutic agent. However, its use is limited by nephrotoxicity. Enalapril is an angiotensin I-converting enzyme inhibitor used for the treatment of hypertension, mainly through the reduction of angiotensin II formation, but also through the increase of kinins h...

Descripción completa

Detalles Bibliográficos
Autores principales: Estrela, Gabriel R., Wasinski, Frederick, Gregnani, Marcos F., Freitas-Lima, Leandro C., Arruda, Adriano C., Morais, Rafael Leite, Malheiros, Denise MAC, Camara, Niels O. S., Pesquero, João Bosco, Bader, Michael, Barros, Carlos Castilho, Araújo, Ronaldo Carvalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257977/
https://www.ncbi.nlm.nih.gov/pubmed/32528973
http://dx.doi.org/10.3389/fmolb.2020.00096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257977/
https://www.ncbi.nlm.nih.gov/pubmed/32528973
http://dx.doi.org/10.3389/fmolb.2020.00096

Ejemplares similares