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Angiotensin-Converting Enzyme Inhibitor Protects Against Cisplatin Nephrotoxicity by Modulating Kinin B1 Receptor Expression and Aminopeptidase P Activity in Mice

Cisplatin is a highly effective chemotherapeutic agent. However, its use is limited by nephrotoxicity. Enalapril is an angiotensin I-converting enzyme inhibitor used for the treatment of hypertension, mainly through the reduction of angiotensin II formation, but also through the increase of kinins h...

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Detalles Bibliográficos
Autores principales:	Estrela, Gabriel R., Wasinski, Frederick, Gregnani, Marcos F., Freitas-Lima, Leandro C., Arruda, Adriano C., Morais, Rafael Leite, Malheiros, Denise MAC, Camara, Niels O. S., Pesquero, João Bosco, Bader, Michael, Barros, Carlos Castilho, Araújo, Ronaldo Carvalho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257977/ https://www.ncbi.nlm.nih.gov/pubmed/32528973 http://dx.doi.org/10.3389/fmolb.2020.00096

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