Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde

During 2015–2016, Cape Verde, an island nation off the coast of West Africa, experienced a Zika virus (ZIKV) outbreak involving 7,580 suspected Zika cases and 18 microcephaly cases. Analysis of the complete genomes of 3 ZIKV isolates from the outbreak indicated the strain was of the Asian (not Afric...

Descripción completa

Detalles Bibliográficos
Autores principales: Faye, Oumar, de Lourdes Monteiro, Maria, Vrancken, Bram, Prot, Matthieu, Lequime, Sebastian, Diarra, Maryam, Ndiaye, Oumar, Valdez, Tomas, Tavarez, Sandra, Ramos, Jessica, da Veiga Leal, Silvânia, Pires, Cecilio, Moreira, Antonio, Tavares, Maria Filomena, Fernandes, Linete, Barreto, Jorge Noel, do Céu Teixeira, Maria, de Lima Mendonça, Maria da Luz, Gomes, Carolina Cardoso da Silva Leite, Castellon, Mariano Salazar, Ma, Laurence, Lemoine, Frédéric, Gámbaro-Roglia, Fabiana, Delaune, Déborah, Fall, Gamou, Fall, Ibrahima Socé, Diop, Mamadou, Sakuntabhai, Anavaj, Loucoubar, Cheikh, Lemey, Philippe, Holmes, Edward C., Faye, Ousmane, Sall, Amadou Alpha, Simon-Loriere, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Synopsis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7258482/
https://www.ncbi.nlm.nih.gov/pubmed/32441631
http://dx.doi.org/10.3201/eid2606.190928
_version_ 1783540091320270848
author Faye, Oumar
de Lourdes Monteiro, Maria
Vrancken, Bram
Prot, Matthieu
Lequime, Sebastian
Diarra, Maryam
Ndiaye, Oumar
Valdez, Tomas
Tavarez, Sandra
Ramos, Jessica
da Veiga Leal, Silvânia
Pires, Cecilio
Moreira, Antonio
Tavares, Maria Filomena
Fernandes, Linete
Barreto, Jorge Noel
do Céu Teixeira, Maria
de Lima Mendonça, Maria da Luz
Gomes, Carolina Cardoso da Silva Leite
Castellon, Mariano Salazar
Ma, Laurence
Lemoine, Frédéric
Gámbaro-Roglia, Fabiana
Delaune, Déborah
Fall, Gamou
Fall, Ibrahima Socé
Diop, Mamadou
Sakuntabhai, Anavaj
Loucoubar, Cheikh
Lemey, Philippe
Holmes, Edward C.
Faye, Ousmane
Sall, Amadou Alpha
Simon-Loriere, Etienne
author_facet Faye, Oumar
de Lourdes Monteiro, Maria
Vrancken, Bram
Prot, Matthieu
Lequime, Sebastian
Diarra, Maryam
Ndiaye, Oumar
Valdez, Tomas
Tavarez, Sandra
Ramos, Jessica
da Veiga Leal, Silvânia
Pires, Cecilio
Moreira, Antonio
Tavares, Maria Filomena
Fernandes, Linete
Barreto, Jorge Noel
do Céu Teixeira, Maria
de Lima Mendonça, Maria da Luz
Gomes, Carolina Cardoso da Silva Leite
Castellon, Mariano Salazar
Ma, Laurence
Lemoine, Frédéric
Gámbaro-Roglia, Fabiana
Delaune, Déborah
Fall, Gamou
Fall, Ibrahima Socé
Diop, Mamadou
Sakuntabhai, Anavaj
Loucoubar, Cheikh
Lemey, Philippe
Holmes, Edward C.
Faye, Ousmane
Sall, Amadou Alpha
Simon-Loriere, Etienne
author_sort Faye, Oumar
collection PubMed
description During 2015–2016, Cape Verde, an island nation off the coast of West Africa, experienced a Zika virus (ZIKV) outbreak involving 7,580 suspected Zika cases and 18 microcephaly cases. Analysis of the complete genomes of 3 ZIKV isolates from the outbreak indicated the strain was of the Asian (not African) lineage. The Cape Verde ZIKV sequences formed a distinct monophylogenetic group and possessed 1–2 (T659A, I756V) unique amino acid changes in the envelope protein. Phylogeographic and serologic evidence support earlier introduction of this lineage into Cape Verde, possibly from northeast Brazil, between June 2014 and August 2015, suggesting cryptic circulation of the virus before the initial wave of cases were detected in October 2015. These findings underscore the utility of genomic-scale epidemiology for outbreak investigations.
format Online
Article
Text
id pubmed-7258482
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-72584822020-06-09 Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde Faye, Oumar de Lourdes Monteiro, Maria Vrancken, Bram Prot, Matthieu Lequime, Sebastian Diarra, Maryam Ndiaye, Oumar Valdez, Tomas Tavarez, Sandra Ramos, Jessica da Veiga Leal, Silvânia Pires, Cecilio Moreira, Antonio Tavares, Maria Filomena Fernandes, Linete Barreto, Jorge Noel do Céu Teixeira, Maria de Lima Mendonça, Maria da Luz Gomes, Carolina Cardoso da Silva Leite Castellon, Mariano Salazar Ma, Laurence Lemoine, Frédéric Gámbaro-Roglia, Fabiana Delaune, Déborah Fall, Gamou Fall, Ibrahima Socé Diop, Mamadou Sakuntabhai, Anavaj Loucoubar, Cheikh Lemey, Philippe Holmes, Edward C. Faye, Ousmane Sall, Amadou Alpha Simon-Loriere, Etienne Emerg Infect Dis Synopsis During 2015–2016, Cape Verde, an island nation off the coast of West Africa, experienced a Zika virus (ZIKV) outbreak involving 7,580 suspected Zika cases and 18 microcephaly cases. Analysis of the complete genomes of 3 ZIKV isolates from the outbreak indicated the strain was of the Asian (not African) lineage. The Cape Verde ZIKV sequences formed a distinct monophylogenetic group and possessed 1–2 (T659A, I756V) unique amino acid changes in the envelope protein. Phylogeographic and serologic evidence support earlier introduction of this lineage into Cape Verde, possibly from northeast Brazil, between June 2014 and August 2015, suggesting cryptic circulation of the virus before the initial wave of cases were detected in October 2015. These findings underscore the utility of genomic-scale epidemiology for outbreak investigations. Centers for Disease Control and Prevention 2020-06 /pmc/articles/PMC7258482/ /pubmed/32441631 http://dx.doi.org/10.3201/eid2606.190928 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Synopsis
Faye, Oumar
de Lourdes Monteiro, Maria
Vrancken, Bram
Prot, Matthieu
Lequime, Sebastian
Diarra, Maryam
Ndiaye, Oumar
Valdez, Tomas
Tavarez, Sandra
Ramos, Jessica
da Veiga Leal, Silvânia
Pires, Cecilio
Moreira, Antonio
Tavares, Maria Filomena
Fernandes, Linete
Barreto, Jorge Noel
do Céu Teixeira, Maria
de Lima Mendonça, Maria da Luz
Gomes, Carolina Cardoso da Silva Leite
Castellon, Mariano Salazar
Ma, Laurence
Lemoine, Frédéric
Gámbaro-Roglia, Fabiana
Delaune, Déborah
Fall, Gamou
Fall, Ibrahima Socé
Diop, Mamadou
Sakuntabhai, Anavaj
Loucoubar, Cheikh
Lemey, Philippe
Holmes, Edward C.
Faye, Ousmane
Sall, Amadou Alpha
Simon-Loriere, Etienne
Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde
title Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde
title_full Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde
title_fullStr Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde
title_full_unstemmed Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde
title_short Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde
title_sort genomic epidemiology of 2015–2016 zika virus outbreak in cape verde
topic Synopsis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7258482/
https://www.ncbi.nlm.nih.gov/pubmed/32441631
http://dx.doi.org/10.3201/eid2606.190928
work_keys_str_mv AT fayeoumar genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT delourdesmonteiromaria genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT vranckenbram genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT protmatthieu genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT lequimesebastian genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT diarramaryam genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT ndiayeoumar genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT valdeztomas genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT tavarezsandra genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT ramosjessica genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT daveigalealsilvania genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT pirescecilio genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT moreiraantonio genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT tavaresmariafilomena genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT fernandeslinete genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT barretojorgenoel genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT doceuteixeiramaria genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT delimamendoncamariadaluz genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT gomescarolinacardosodasilvaleite genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT castellonmarianosalazar genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT malaurence genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT lemoinefrederic genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT gambarorogliafabiana genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT delaunedeborah genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT fallgamou genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT fallibrahimasoce genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT diopmamadou genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT sakuntabhaianavaj genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT loucoubarcheikh genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT lemeyphilippe genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT holmesedwardc genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT fayeousmane genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT sallamadoualpha genomicepidemiologyof20152016zikavirusoutbreakincapeverde
AT simonloriereetienne genomicepidemiologyof20152016zikavirusoutbreakincapeverde

Ejemplares similares