Improvement of Pain Relief of Fentanyl Citrate Drug Encapsulated in Nanostructured Lipid Carrier: Drug Formulation, Parameter Optimization, in vitro and in vivo Studies

INTRODUCTION: In this study, the encapsulation of fentanyl citrate as an opioid drug with hydrophobic nature in the nanostructured lipid carrier (NLC) is performed. METHODS: For encapsulation of fentanyl citrate drug, hot homogenization method is used. The pharmacokinetics of encapsulated fentany...

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Detalles Bibliográficos
Autores principales: Bahrami, Mohammad Amin, Farhadian, Nafiseh, Karimi, Mohammad, Forouzan, Arash, Masoumi, Kambiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259451/
https://www.ncbi.nlm.nih.gov/pubmed/32546968
http://dx.doi.org/10.2147/DDDT.S235474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259451/
https://www.ncbi.nlm.nih.gov/pubmed/32546968
http://dx.doi.org/10.2147/DDDT.S235474

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