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Improvement of Pain Relief of Fentanyl Citrate Drug Encapsulated in Nanostructured Lipid Carrier: Drug Formulation, Parameter Optimization, in vitro and in vivo Studies

INTRODUCTION: In this study, the encapsulation of fentanyl citrate as an opioid drug with hydrophobic nature in the nanostructured lipid carrier (NLC) is performed. METHODS: For encapsulation of fentanyl citrate drug, hot homogenization method is used. The pharmacokinetics of encapsulated fentany...

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Detalles Bibliográficos
Autores principales:	Bahrami, Mohammad Amin, Farhadian, Nafiseh, Karimi, Mohammad, Forouzan, Arash, Masoumi, Kambiz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259451/ https://www.ncbi.nlm.nih.gov/pubmed/32546968 http://dx.doi.org/10.2147/DDDT.S235474

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