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Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2(C342Y/+) mouse models of Crouzon syndrome

Craniosynostosis is the premature fusion of cranial bones. The goal of this study was to determine if delivery of recombinant tissue nonspecific alkaline phosphatase (TNAP) could prevent or diminish the severity of craniosynostosis in a C57BL/6 FGFR2(C342Y/+) model of neonatal onset craniosynostosis...

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Detalles Bibliográficos
Autores principales:	Nam, Hwa Kyung, Vesela, Iva, Schutte, Sara Dean, Hatch, Nan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259715/ https://www.ncbi.nlm.nih.gov/pubmed/32470062 http://dx.doi.org/10.1371/journal.pone.0234073

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