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Differential effects of Fe(2+) and Fe(3+) on osteoblasts and the effects of 1,25(OH)(2)D(3), deferiprone and extracellular calcium on osteoblast viability under iron-overloaded conditions
One of the potential contributing factors for iron overload-induced osteoporosis is the iron toxicity on bone forming cells, osteoblasts. In this study, the comparative effects of Fe(3+) and Fe(2+) on osteoblast differentiation and mineralization were studied in UMR-106 osteoblast cells by using fer...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259719/ https://www.ncbi.nlm.nih.gov/pubmed/32470038 http://dx.doi.org/10.1371/journal.pone.0234009 |