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Constructing a human complex type N-linked glycosylation pathway in Kluyveromyces marxianus
Glycosylation can affect various protein properties such as stability, biological activity, and immunogenicity. To produce human therapeutic proteins, a host that can produce glycoproteins with correct glycan structures is required. Microbial expression systems offer economical, rapid and serum-free...
Autores principales: | Lee, Ming-Hsuan, Hsu, Tsui-Ling, Lin, Jinn-Jy, Lin, Yu-Ju, Kao, Yi-Ying, Chang, Jui-Jen, Li, Wen-Hsiung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259728/ https://www.ncbi.nlm.nih.gov/pubmed/32469948 http://dx.doi.org/10.1371/journal.pone.0233492 |
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