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Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs
Despite over a billion years of evolutionary divergence, several thousand human genes possess clearly identifiable orthologs in yeast, and many have undergone lineage-specific duplications in one or both lineages. These duplicated genes may have been free to diverge in function since their expansion...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259792/ https://www.ncbi.nlm.nih.gov/pubmed/32421706 http://dx.doi.org/10.1371/journal.pbio.3000627 |