Introductions and early spread of SARS-CoV-2 in the New York City area

New York City (NYC) has emerged as one of the epicenters of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus that causes coronavir...

Descripción completa

Detalles Bibliográficos
Autores principales: Gonzalez-Reiche, Ana S., Hernandez, Matthew M., Sullivan, Mitchell J., Ciferri, Brianne, Alshammary, Hala, Obla, Ajay, Fabre, Shelcie, Kleiner, Giulio, Polanco, Jose, Khan, Zenab, Alburquerque, Bremy, van de Guchte, Adriana, Dutta, Jayeeta, Francoeur, Nancy, Melo, Betsaida Salom, Oussenko, Irina, Deikus, Gintaras, Soto, Juan, Sridhar, Shwetha Hara, Wang, Ying-Chih, Twyman, Kathryn, Kasarskis, Andrew, Altman, Deena R., Smith, Melissa, Sebra, Robert, Aberg, Judith, Krammer, Florian, García-Sastre, Adolfo, Luksza, Marta, Patel, Gopi, Paniz-Mondolfi, Alberto, Gitman, Melissa, Sordillo, Emilia Mia, Simon, Viviana, van Bakel, Harm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259823/
https://www.ncbi.nlm.nih.gov/pubmed/32471856
http://dx.doi.org/10.1126/science.abc1917
_version_ 1783540210397609984
author Gonzalez-Reiche, Ana S.
Hernandez, Matthew M.
Sullivan, Mitchell J.
Ciferri, Brianne
Alshammary, Hala
Obla, Ajay
Fabre, Shelcie
Kleiner, Giulio
Polanco, Jose
Khan, Zenab
Alburquerque, Bremy
van de Guchte, Adriana
Dutta, Jayeeta
Francoeur, Nancy
Melo, Betsaida Salom
Oussenko, Irina
Deikus, Gintaras
Soto, Juan
Sridhar, Shwetha Hara
Wang, Ying-Chih
Twyman, Kathryn
Kasarskis, Andrew
Altman, Deena R.
Smith, Melissa
Sebra, Robert
Aberg, Judith
Krammer, Florian
García-Sastre, Adolfo
Luksza, Marta
Patel, Gopi
Paniz-Mondolfi, Alberto
Gitman, Melissa
Sordillo, Emilia Mia
Simon, Viviana
van Bakel, Harm
author_facet Gonzalez-Reiche, Ana S.
Hernandez, Matthew M.
Sullivan, Mitchell J.
Ciferri, Brianne
Alshammary, Hala
Obla, Ajay
Fabre, Shelcie
Kleiner, Giulio
Polanco, Jose
Khan, Zenab
Alburquerque, Bremy
van de Guchte, Adriana
Dutta, Jayeeta
Francoeur, Nancy
Melo, Betsaida Salom
Oussenko, Irina
Deikus, Gintaras
Soto, Juan
Sridhar, Shwetha Hara
Wang, Ying-Chih
Twyman, Kathryn
Kasarskis, Andrew
Altman, Deena R.
Smith, Melissa
Sebra, Robert
Aberg, Judith
Krammer, Florian
García-Sastre, Adolfo
Luksza, Marta
Patel, Gopi
Paniz-Mondolfi, Alberto
Gitman, Melissa
Sordillo, Emilia Mia
Simon, Viviana
van Bakel, Harm
author_sort Gonzalez-Reiche, Ana S.
collection PubMed
description New York City (NYC) has emerged as one of the epicenters of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus that causes coronavirus disease 2019 (COVID-19) in patients seeking care at the Mount Sinai Health System. Phylogenetic analysis of 84 distinct SARS-CoV-2 genomes indicates multiple, independent, but isolated introductions mainly from Europe and other parts of the United States. Moreover, we found evidence for community transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different neighborhoods of the city.
format Online
Article
Text
id pubmed-7259823
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher American Association for the Advancement of Science
record_format MEDLINE/PubMed
spelling pubmed-72598232020-06-12 Introductions and early spread of SARS-CoV-2 in the New York City area Gonzalez-Reiche, Ana S. Hernandez, Matthew M. Sullivan, Mitchell J. Ciferri, Brianne Alshammary, Hala Obla, Ajay Fabre, Shelcie Kleiner, Giulio Polanco, Jose Khan, Zenab Alburquerque, Bremy van de Guchte, Adriana Dutta, Jayeeta Francoeur, Nancy Melo, Betsaida Salom Oussenko, Irina Deikus, Gintaras Soto, Juan Sridhar, Shwetha Hara Wang, Ying-Chih Twyman, Kathryn Kasarskis, Andrew Altman, Deena R. Smith, Melissa Sebra, Robert Aberg, Judith Krammer, Florian García-Sastre, Adolfo Luksza, Marta Patel, Gopi Paniz-Mondolfi, Alberto Gitman, Melissa Sordillo, Emilia Mia Simon, Viviana van Bakel, Harm Science Reports New York City (NYC) has emerged as one of the epicenters of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus that causes coronavirus disease 2019 (COVID-19) in patients seeking care at the Mount Sinai Health System. Phylogenetic analysis of 84 distinct SARS-CoV-2 genomes indicates multiple, independent, but isolated introductions mainly from Europe and other parts of the United States. Moreover, we found evidence for community transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different neighborhoods of the city. American Association for the Advancement of Science 2020-07-17 2020-05-29 /pmc/articles/PMC7259823/ /pubmed/32471856 http://dx.doi.org/10.1126/science.abc1917 Text en Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). http://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Reports
Gonzalez-Reiche, Ana S.
Hernandez, Matthew M.
Sullivan, Mitchell J.
Ciferri, Brianne
Alshammary, Hala
Obla, Ajay
Fabre, Shelcie
Kleiner, Giulio
Polanco, Jose
Khan, Zenab
Alburquerque, Bremy
van de Guchte, Adriana
Dutta, Jayeeta
Francoeur, Nancy
Melo, Betsaida Salom
Oussenko, Irina
Deikus, Gintaras
Soto, Juan
Sridhar, Shwetha Hara
Wang, Ying-Chih
Twyman, Kathryn
Kasarskis, Andrew
Altman, Deena R.
Smith, Melissa
Sebra, Robert
Aberg, Judith
Krammer, Florian
García-Sastre, Adolfo
Luksza, Marta
Patel, Gopi
Paniz-Mondolfi, Alberto
Gitman, Melissa
Sordillo, Emilia Mia
Simon, Viviana
van Bakel, Harm
Introductions and early spread of SARS-CoV-2 in the New York City area
title Introductions and early spread of SARS-CoV-2 in the New York City area
title_full Introductions and early spread of SARS-CoV-2 in the New York City area
title_fullStr Introductions and early spread of SARS-CoV-2 in the New York City area
title_full_unstemmed Introductions and early spread of SARS-CoV-2 in the New York City area
title_short Introductions and early spread of SARS-CoV-2 in the New York City area
title_sort introductions and early spread of sars-cov-2 in the new york city area
topic Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259823/
https://www.ncbi.nlm.nih.gov/pubmed/32471856
http://dx.doi.org/10.1126/science.abc1917
work_keys_str_mv AT gonzalezreicheanas introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT hernandezmatthewm introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT sullivanmitchellj introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT ciferribrianne introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT alshammaryhala introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT oblaajay introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT fabreshelcie introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT kleinergiulio introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT polancojose introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT khanzenab introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT alburquerquebremy introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT vandeguchteadriana introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT duttajayeeta introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT francoeurnancy introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT melobetsaidasalom introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT oussenkoirina introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT deikusgintaras introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT sotojuan introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT sridharshwethahara introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT wangyingchih introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT twymankathryn introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT kasarskisandrew introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT altmandeenar introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT smithmelissa introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT sebrarobert introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT abergjudith introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT krammerflorian introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT garciasastreadolfo introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT lukszamarta introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT patelgopi introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT panizmondolfialberto introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT gitmanmelissa introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT sordilloemiliamia introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT simonviviana introductionsandearlyspreadofsarscov2inthenewyorkcityarea
AT vanbakelharm introductionsandearlyspreadofsarscov2inthenewyorkcityarea

Ejemplares similares