Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

The H2A.Z histone variant, a genome-wide hallmark of permissive chromatin, is enriched near transcription start sites in all eukaryotes. H2A.Z is deposited by the SWR1 chromatin remodeler and evicted by unclear mechanisms. We tracked H2A.Z in living yeast at single-molecule resolution, and found tha...

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Detalles Bibliográficos
Autores principales: Ranjan, Anand, Nguyen, Vu Q, Liu, Sheng, Wisniewski, Jan, Kim, Jee Min, Tang, Xiaona, Mizuguchi, Gaku, Elalaoui, Ejlal, Nickels, Timothy J, Jou, Vivian, English, Brian P, Zheng, Qinsi, Luk, Ed, Lavis, Luke D, Lionnet, Timothee, Wu, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259955/
https://www.ncbi.nlm.nih.gov/pubmed/32338606
http://dx.doi.org/10.7554/eLife.55667

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