MeCP2 in cholinergic interneurons of nucleus accumbens regulates fear learning

Methyl-CpG-binding protein 2 (MeCP2) encoded by the MECP2 gene is a transcriptional regulator whose mutations cause Rett syndrome (RTT). Mecp2-deficient mice show fear regulation impairment; however, the cellular and molecular mechanisms underlying this abnormal behavior are largely uncharacterized....

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Zhu, Yi, Cao, Shu-Xia, Sun, Peng, Yang, Jian-Ming, Xia, Yan-Fang, Xie, Shi-Ze, Yu, Xiao-Dan, Fu, Jia-Yu, Shen, Chen-Jie, He, Hai-Yang, Pan, Hao-Qi, Chen, Xiao-Juan, Wang, Hao, Li, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259956/
https://www.ncbi.nlm.nih.gov/pubmed/32420873
http://dx.doi.org/10.7554/eLife.55342

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