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Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway
Extensive research over the past decades has identified integrins to be the primary transmembrane receptors that enable cells to respond to external mechanical cues. We reveal here a mechanism whereby syndecan-4 tunes cell mechanics in response to localised tension via a coordinated mechanochemical...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260055/ https://www.ncbi.nlm.nih.gov/pubmed/31907416 http://dx.doi.org/10.1038/s41563-019-0567-1 |