Genome-Wide Meta-analysis of Variant-by-Diuretic Interactions as Modulators of Lipid Traits in Persons of European and African Ancestry

Hypertension (HTN) is a significant risk factor for cardiovascular morbidity and mortality. Metabolic abnormalities, including adverse cholesterol and triglycerides (TG) profiles, are frequent comorbid findings with HTN and contribute to cardiovascular disease. Diuretics, which are used to treat HTN...

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Detalles Bibliográficos
Autores principales: de las Fuentes, L, Sung, YJ, Sitlani, CM, Avery, CL, Bartz, TM, de Keyser, C, Evans, DS, Li, X, Musani, SK, Ruiter, R, Smith, AV, Sun, F, Trompet, S, Xu, H, Arnett, DK, Bis, JC, Broeckel, U, Busch, EL., Chen, YI, Correa, A, Cummings, SR, Floyd, JS, Ford, I, Guo, X, Harris, TB, Ikram, MA, Lange, L, Launer, LJ, Reiner, AP, Schwander, K, Smith, NL, Sotoodehnia, N, Stewart, JD, Stott, DJ, Stürmer, T, Taylor, KD, Uitterlinden, A, Vasan, RS, Wiggins, KL, Cupples, LA, Gudnason, V, Heckbert, SR, Jukema, JW, Liu, Y, Psaty, BM, Rao, DC, Rotter, JI, Stricker, B, Wilson, JG, Whitsel, EA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260079/
https://www.ncbi.nlm.nih.gov/pubmed/31806883
http://dx.doi.org/10.1038/s41397-019-0132-y

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