BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer

The cytosolic branched chain aminotransferase (BCATc) protein has been found to be highly expressed in breast cancer subtypes, including triple negative breast cancer (TNBC), compared with normal breast tissue. The catabolism of branched-chain amino acids (BCAAs) by BCATc leads to the production of...

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Detalles Bibliográficos
Autores principales: Shafei, Mai Ahmed, Forshaw, Thomas, Davis, Jasmine, Flemban, Arwa, Qualtrough, David, Dean, Sarah, Perks, Claire, Dong, Ming, Newman, Robert, Conway, Myra Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260123/
https://www.ncbi.nlm.nih.gov/pubmed/32523652
http://dx.doi.org/10.18632/oncotarget.27607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260123/
https://www.ncbi.nlm.nih.gov/pubmed/32523652
http://dx.doi.org/10.18632/oncotarget.27607

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