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BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer
The cytosolic branched chain aminotransferase (BCATc) protein has been found to be highly expressed in breast cancer subtypes, including triple negative breast cancer (TNBC), compared with normal breast tissue. The catabolism of branched-chain amino acids (BCAAs) by BCATc leads to the production of...
Autores principales: | Shafei, Mai Ahmed, Forshaw, Thomas, Davis, Jasmine, Flemban, Arwa, Qualtrough, David, Dean, Sarah, Perks, Claire, Dong, Ming, Newman, Robert, Conway, Myra Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260123/ https://www.ncbi.nlm.nih.gov/pubmed/32523652 http://dx.doi.org/10.18632/oncotarget.27607 |
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