Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation

Endosomal sorting complexes for transport-III (ESCRT-III) assemble in vivo onto membranes with negative Gaussian curvature. How membrane shape influences ESCRT-III polymerization and how ESCRT-III shapes membranes is yet unclear. Human core ESCRT-III proteins, CHMP4B, CHMP2A, CHMP2B and CHMP3 are us...

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Detalles Bibliográficos
Autores principales: Bertin, Aurélie, de Franceschi, Nicola, de la Mora, Eugenio, Maiti, Sourav, Alqabandi, Maryam, Miguet, Nolwen, di Cicco, Aurélie, Roos, Wouter H., Mangenot, Stéphanie, Weissenhorn, Winfried, Bassereau, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260177/
https://www.ncbi.nlm.nih.gov/pubmed/32471988
http://dx.doi.org/10.1038/s41467-020-16368-5

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