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Evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries
The manipulation of superparamagnetic microbeads for lab-on-a-chip applications relies on the steering of microbeads across an altering stray field landscape on top of soft magnetic parent structures. Using ab initio principles, we show three-dimensional simulations forecasting the controlled moveme...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260204/ https://www.ncbi.nlm.nih.gov/pubmed/32472020 http://dx.doi.org/10.1038/s41598-020-65380-8 |
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author | Klingbeil, Finn Block, Findan Sajjad, Umer Holländer, Rasmus B. Deshpande, Sughosh McCord, Jeffrey |
author_facet | Klingbeil, Finn Block, Findan Sajjad, Umer Holländer, Rasmus B. Deshpande, Sughosh McCord, Jeffrey |
author_sort | Klingbeil, Finn |
collection | PubMed |
description | The manipulation of superparamagnetic microbeads for lab-on-a-chip applications relies on the steering of microbeads across an altering stray field landscape on top of soft magnetic parent structures. Using ab initio principles, we show three-dimensional simulations forecasting the controlled movement of microbeads. Simulated aspects of microbead behaviour include the looping and lifting of microbeads around a magnetic circular structure, the flexible bead movement along symmetrically distributed triangular structures, and the dragging of magnetic beads across an array of exchange biased magnetic microstripes. The unidirectional motion of microbeads across a string of oval elements is predicted by simulations and validated experimentally. Each of the simulations matches the experimental results, proving the robustness and accuracy of the applied numerical method. The computer experiments provide details on the particle motion not accessible by experiments. The simulation capabilities prove to be an essential part for the estimation of future lab-on-chip designs. |
format | Online Article Text |
id | pubmed-7260204 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-72602042020-06-05 Evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries Klingbeil, Finn Block, Findan Sajjad, Umer Holländer, Rasmus B. Deshpande, Sughosh McCord, Jeffrey Sci Rep Article The manipulation of superparamagnetic microbeads for lab-on-a-chip applications relies on the steering of microbeads across an altering stray field landscape on top of soft magnetic parent structures. Using ab initio principles, we show three-dimensional simulations forecasting the controlled movement of microbeads. Simulated aspects of microbead behaviour include the looping and lifting of microbeads around a magnetic circular structure, the flexible bead movement along symmetrically distributed triangular structures, and the dragging of magnetic beads across an array of exchange biased magnetic microstripes. The unidirectional motion of microbeads across a string of oval elements is predicted by simulations and validated experimentally. Each of the simulations matches the experimental results, proving the robustness and accuracy of the applied numerical method. The computer experiments provide details on the particle motion not accessible by experiments. The simulation capabilities prove to be an essential part for the estimation of future lab-on-chip designs. Nature Publishing Group UK 2020-05-29 /pmc/articles/PMC7260204/ /pubmed/32472020 http://dx.doi.org/10.1038/s41598-020-65380-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Klingbeil, Finn Block, Findan Sajjad, Umer Holländer, Rasmus B. Deshpande, Sughosh McCord, Jeffrey Evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries |
title | Evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries |
title_full | Evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries |
title_fullStr | Evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries |
title_full_unstemmed | Evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries |
title_short | Evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries |
title_sort | evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260204/ https://www.ncbi.nlm.nih.gov/pubmed/32472020 http://dx.doi.org/10.1038/s41598-020-65380-8 |
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