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SIRT1 directly activates autophagy in human chondrocytes
Osteoarthritis (OA) is the most common form of arthritis worldwide with no effective treatment. Ageing is the primary risk factor for OA. We sought to investigate if there is a distinct and functional convergence of ageing-related mechanisms SIRT1 and autophagy in chondrocytes. Our results show that...
Autores principales: | Sacitharan, Pradeep K., Bou-Gharios, George, Edwards, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260231/ https://www.ncbi.nlm.nih.gov/pubmed/32528730 http://dx.doi.org/10.1038/s41420-020-0277-0 |
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