COVID-19-associated acute disseminated encephalomyelitis (ADEM)

A 51-year-old woman with COVID-19 infection developed coma and an impaired oculocephalic response to one side. MRI of the brain demonstrated acute multifocal demyelinating lesions, and CSF testing did not identify a direct cerebral infection. High-dose steroids followed by a course of IVIG was admin...

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Detalles Bibliográficos
Autores principales: Parsons, Timothy, Banks, Sarah, Bae, Chay, Gelber, Joel, Alahmadi, Hussein, Tichauer, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Letter to the Editors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260459/
https://www.ncbi.nlm.nih.gov/pubmed/32474657
http://dx.doi.org/10.1007/s00415-020-09951-9
Descripción
Sumario:A 51-year-old woman with COVID-19 infection developed coma and an impaired oculocephalic response to one side. MRI of the brain demonstrated acute multifocal demyelinating lesions, and CSF testing did not identify a direct cerebral infection. High-dose steroids followed by a course of IVIG was administered, and the patient regained consciousness over the course of several weeks. As more patients reach the weeks after initial infection with COVID-19, acute disseminated encephalomyelitis should be considered a potentially treatable cause of profound encephalopathy or multifocal neurological deficits.

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