COVID-19-associated acute disseminated encephalomyelitis (ADEM)

A 51-year-old woman with COVID-19 infection developed coma and an impaired oculocephalic response to one side. MRI of the brain demonstrated acute multifocal demyelinating lesions, and CSF testing did not identify a direct cerebral infection. High-dose steroids followed by a course of IVIG was admin...

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Autores principales: Parsons, Timothy, Banks, Sarah, Bae, Chay, Gelber, Joel, Alahmadi, Hussein, Tichauer, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Letter to the Editors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260459/
https://www.ncbi.nlm.nih.gov/pubmed/32474657
http://dx.doi.org/10.1007/s00415-020-09951-9
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author Parsons, Timothy
Banks, Sarah
Bae, Chay
Gelber, Joel
Alahmadi, Hussein
Tichauer, Matthew
author_facet Parsons, Timothy
Banks, Sarah
Bae, Chay
Gelber, Joel
Alahmadi, Hussein
Tichauer, Matthew
author_sort Parsons, Timothy
collection PubMed
description A 51-year-old woman with COVID-19 infection developed coma and an impaired oculocephalic response to one side. MRI of the brain demonstrated acute multifocal demyelinating lesions, and CSF testing did not identify a direct cerebral infection. High-dose steroids followed by a course of IVIG was administered, and the patient regained consciousness over the course of several weeks. As more patients reach the weeks after initial infection with COVID-19, acute disseminated encephalomyelitis should be considered a potentially treatable cause of profound encephalopathy or multifocal neurological deficits.
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spelling pubmed-72604592020-06-01 COVID-19-associated acute disseminated encephalomyelitis (ADEM) Parsons, Timothy Banks, Sarah Bae, Chay Gelber, Joel Alahmadi, Hussein Tichauer, Matthew J Neurol Letter to the Editors A 51-year-old woman with COVID-19 infection developed coma and an impaired oculocephalic response to one side. MRI of the brain demonstrated acute multifocal demyelinating lesions, and CSF testing did not identify a direct cerebral infection. High-dose steroids followed by a course of IVIG was administered, and the patient regained consciousness over the course of several weeks. As more patients reach the weeks after initial infection with COVID-19, acute disseminated encephalomyelitis should be considered a potentially treatable cause of profound encephalopathy or multifocal neurological deficits. Springer Berlin Heidelberg 2020-05-30 2020 /pmc/articles/PMC7260459/ /pubmed/32474657 http://dx.doi.org/10.1007/s00415-020-09951-9 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Letter to the Editors
Parsons, Timothy
Banks, Sarah
Bae, Chay
Gelber, Joel
Alahmadi, Hussein
Tichauer, Matthew
COVID-19-associated acute disseminated encephalomyelitis (ADEM)
title COVID-19-associated acute disseminated encephalomyelitis (ADEM)
title_full COVID-19-associated acute disseminated encephalomyelitis (ADEM)
title_fullStr COVID-19-associated acute disseminated encephalomyelitis (ADEM)
title_full_unstemmed COVID-19-associated acute disseminated encephalomyelitis (ADEM)
title_short COVID-19-associated acute disseminated encephalomyelitis (ADEM)
title_sort covid-19-associated acute disseminated encephalomyelitis (adem)
topic Letter to the Editors
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260459/
https://www.ncbi.nlm.nih.gov/pubmed/32474657
http://dx.doi.org/10.1007/s00415-020-09951-9
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