Cargando…

Glycine Improves Ischemic Stroke Through miR-19a-3p/AMPK/GSK-3β/HO-1 Pathway

PURPOSE: To explore the molecular mechanism of glycine in improving ischemic stroke. PATIENTS AND METHODS: The serum samples of patients with ischemic stroke and healthy people were compared. The ischemic stroke model of PC12 cells was established by oxygen-glucose deprivation (OGD). qPCR quantified...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Zhong-Jun, Zhao, Xu-Sheng, Fan, Tie-Ping, Qi, Heng-Xu, Li, Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260540/ https://www.ncbi.nlm.nih.gov/pubmed/32546967 http://dx.doi.org/10.2147/DDDT.S248104

Ejemplares similares

Neuroprotective effect of Apelin 13 on ischemic stroke by activating AMPK/GSK-3β/Nrf2 signaling
por: Duan, Jialin, et al.
Publicado: (2019)

MiR-27a Facilitates Breast Cancer Progression via GSK-3β
por: Chen, Huijin, et al.
Publicado: (2020)

Empagliflozin Inhibits Hepatic Gluconeogenesis and Increases Glycogen Synthesis by AMPK/CREB/GSK3β Signalling Pathway
por: Yu, Xiaochen, et al.
Publicado: (2022)

miR-4721, Induced by EBV-miR-BART22, Targets GSK3β to Enhance the Tumorigenic Capacity of NPC through the WNT/β-catenin Pathway
por: Tang, ZiBo, et al.
Publicado: (2020)

Increased Brain-Specific MiR-9 and MiR-124 in the Serum Exosomes of Acute Ischemic Stroke Patients
por: Ji, Qiuhong, et al.
Publicado: (2016)

Effects of regulating miR-132 mediated GSK-3β on learning and memory function in mice
por: Liu, Gang, et al.
Publicado: (2020)

Ginkgolide K attenuates neuronal injury after ischemic stroke by inhibiting mitochondrial fission and GSK-3β-dependent increases in mitochondrial membrane permeability
por: Zhou, Xu, et al.
Publicado: (2017)

GSK-3β Promotes Cell Migration and Inhibits Autophagy by Mediating the AMPK Pathway in Breast Cancer
por: Guo, Lu, et al.
Publicado: (2019)

miR-632 Promotes Laryngeal Carcinoma Cell Proliferation, Migration, and Invasion Through Negative Regulation of GSK3β
por: Zhou, Zhong-xin, et al.
Publicado: (2020)

Decreased miR-132 plays a crucial role in diabetic encephalopathy by regulating the GSK-3β/Tau pathway
por: Shi, Li, et al.
Publicado: (2020)

1,25-D3 attenuates cerebral ischemia injury by regulating mitochondrial metabolism via the AMPK/AKT/GSK3β pathway
por: Li, Yutian, et al.
Publicado: (2022)

miR-146a promotes growth of osteosarcoma cells by targeting ZNRF3/GSK-3β/β-catenin signaling pathway
por: Zhou, Chun, et al.
Publicado: (2017)

Novel Reporter Alleles of GSK-3α and GSK-3β
por: Barrell, William B., et al.
Publicado: (2012)

miR-135b Contributes to the Radioresistance by Targeting GSK3β in Human Glioblastoma Multiforme Cells
por: Xiao, Songhua, et al.
Publicado: (2014)

Inhibition of GSK3β Reduces Ectopic Lipid Accumulation and Induces Autophagy by The AMPK Pathway in Goat Muscle Satellite Cells
por: Wang, Linjie, et al.
Publicado: (2019)

Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis
por: Ríos, Juvenal A., et al.
Publicado: (2018)

Different expression of GSK3β and pS9GSK3β depending on phenotype of cervical cancer: possible association of GSK3β with squamous cell carcinoma and pS9GSK3β with adenocarcinoma
por: Ahn, Kwanghee, et al.
Publicado: (2019)

Association of miR-21, miR-126 and miR-605 gene polymorphisms with ischemic stroke risk
por: Xiang, Yang, et al.
Publicado: (2017)

Dysregulated levels of glycogen synthase kinase-3β (GSK-3β) and miR-135 in peripheral blood samples of cases with nephrotic syndrome
por: Ardalan, Mohammadreza, et al.
Publicado: (2020)

Oleanolic Acid Alleviates Cerebral Ischemia/Reperfusion Injury via Regulation of the GSK-3β/HO-1 Signaling Pathway
por: Lin, Kaili, et al.
Publicado: (2021)

GSK3β Serine 389 Phosphorylation Modulates Cardiomyocyte Hypertrophy and Ischemic Injury
por: Vainio, Laura, et al.
Publicado: (2021)

MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer
por: Ke, Xixian, et al.
Publicado: (2017)

MiR-26a-5p inhibits GSK3β expression and promotes cardiac hypertrophy in vitro
por: Tang, Liqun, et al.
Publicado: (2020)

Girdin acts as an oncogene in gastric cancer by regulating AKT/GSK3β/β-catenin signaling
por: Wang, Yun, et al.
Publicado: (2023)

lncRNA MEG3 Promotes PDK4/GSK-3β/β-Catenin Axis in MEFs by Targeting miR-532-5p
por: Yang, Yuan-Yuan, et al.
Publicado: (2023)

AMPK: Potential Therapeutic Target for Ischemic Stroke
por: Jiang, Shuai, et al.
Publicado: (2018)

Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells
por: Weikel, Karen A., et al.
Publicado: (2016)

Corilagin alleviates acetaminophen-induced hepatotoxicity via enhancing the AMPK/GSK3β-Nrf2 signaling pathway
por: Lv, Hongming, et al.
Publicado: (2019)

Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β
por: Cymerman, Iwona A., et al.
Publicado: (2015)

GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation
por: Gozdz, Agata, et al.
Publicado: (2017)

Exploring the potential value of miR-148b-3p, miR-151b and miR-27b-3p as biomarkers in acute ischemic stroke
por: Cheng, Xiuli, et al.
Publicado: (2018)

miR-9 and miR-124 synergistically affect regulation of dendritic branching via the AKT/GSK3β pathway by targeting Rap2a
por: Xue, Qian, et al.
Publicado: (2016)

GSK-3β and memory formation
por: Takashima, Akihiko
Publicado: (2012)

GSK3β and aging liver
por: Jin, Jingling, et al.
Publicado: (2009)

GSK3β and the aging kidney
por: Kreidberg, Jordan A., et al.
Publicado: (2022)

MiR-1246 Promotes Metastasis and Invasion of A549 cells by Targeting GSK-3β‒Mediated Wnt/β-Catenin Pathway
por: Yang, Fan, et al.
Publicado: (2019)

Naringin attenuates acute myocardial ischemia-reperfusion injury via miR- 126/GSK-3β/β-catenin signaling pathway
por: Guo, Xiuhui, et al.
Publicado: (2022)

Downregulation of GSK3β by miR-544a to maintain self-renewal ability of lung caner stem cells
por: MO, XIAO-MEI, et al.
Publicado: (2014)

Gsk-3β Inhibitors Mimic the Cardioprotection Mediated by Ischemic Pre- and Postconditioning in Hypertensive Rats
por: González Arbeláez, Luisa F., et al.
Publicado: (2013)

miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis
por: Yang, Ya-Ling, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_nv9687jqn3kvtfporhvbeagtl2