In Vitro and Animal Models for SARS-CoV-2 research

Basic research on SARS-CoV-2 is essential to understand its detailed pathophysiology and identify best drug targets. Models that can faithfully reproduce the viral life cycle and reproduce the pathology of COVID-19 are required. Here, we briefly review the cell lines, organoids, and animal models th...

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Detalles Bibliográficos
Autor principal: Takayama, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260555/
https://www.ncbi.nlm.nih.gov/pubmed/32553545
http://dx.doi.org/10.1016/j.tips.2020.05.005
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author Takayama, Kazuo
author_facet Takayama, Kazuo
author_sort Takayama, Kazuo
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description Basic research on SARS-CoV-2 is essential to understand its detailed pathophysiology and identify best drug targets. Models that can faithfully reproduce the viral life cycle and reproduce the pathology of COVID-19 are required. Here, we briefly review the cell lines, organoids, and animal models that are currently being used in COVID-19 research.
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spelling pubmed-72605552020-06-01 In Vitro and Animal Models for SARS-CoV-2 research Takayama, Kazuo Trends Pharmacol Sci Article Basic research on SARS-CoV-2 is essential to understand its detailed pathophysiology and identify best drug targets. Models that can faithfully reproduce the viral life cycle and reproduce the pathology of COVID-19 are required. Here, we briefly review the cell lines, organoids, and animal models that are currently being used in COVID-19 research. Elsevier Ltd. 2020-08 2020-05-30 /pmc/articles/PMC7260555/ /pubmed/32553545 http://dx.doi.org/10.1016/j.tips.2020.05.005 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Takayama, Kazuo
In Vitro and Animal Models for SARS-CoV-2 research
title In Vitro and Animal Models for SARS-CoV-2 research
title_full In Vitro and Animal Models for SARS-CoV-2 research
title_fullStr In Vitro and Animal Models for SARS-CoV-2 research
title_full_unstemmed In Vitro and Animal Models for SARS-CoV-2 research
title_short In Vitro and Animal Models for SARS-CoV-2 research
title_sort in vitro and animal models for sars-cov-2 research
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260555/
https://www.ncbi.nlm.nih.gov/pubmed/32553545
http://dx.doi.org/10.1016/j.tips.2020.05.005
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