Propagation of Pathological α-Synuclein from the Urogenital Tract to the Brain Initiates MSA-like Syndrome

The neuropathological feature of multiple system atrophy (MSA), a fatal adult-onset disorder without effective therapy, is the accumulation of pathological α-synuclein (α-Syn) in the central nervous system (CNS). Here we show that pathological α-Syn exists in nerve terminals in detrusor and external...

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Detalles Bibliográficos
Autores principales: Ding, Xuebing, Zhou, Lebo, Jiang, Xiaoyi, Liu, Han, Yao, Jing, Zhang, Rui, Liang, Dongxiao, Wang, Fengfei, Ma, Mingming, Tang, Beisha, Wu, Erxi, Teng, Junfang, Wang, Xuejing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260590/
https://www.ncbi.nlm.nih.gov/pubmed/32470898
http://dx.doi.org/10.1016/j.isci.2020.101166

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