Brilliant blue G, a P2X7 receptor antagonist, attenuates early phase of renal inflammation, interstitial fibrosis and is associated with renal cell proliferation in ureteral obstruction in rats

BACKGROUND: Previous study showed that purinergic P2X7 receptors (P2X7R) reach the highest expression in the first week after unilateral ureteral obstruction (UUO) in mice, and are involved in the process of inflammation, apoptosis and fibrosis of renal tissue. We, herein, document the role of purin...

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Detalles Bibliográficos
Autores principales: Pereira, José Monteiro Sad, Barreira, André Luis, Gomes, Conrado Rodrigues, Ornellas, Felipe Mateus, Ornellas, Débora Santos, Miranda, Luiz Carlos, Cardoso, Lucio Ronaldo, Coutinho-Silva, Robson, Schanaider, Alberto, Morales, Marcelo M., Leite, Maurilo, Takiya, Christina Maeda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260756/
https://www.ncbi.nlm.nih.gov/pubmed/32471386
http://dx.doi.org/10.1186/s12882-020-01861-2

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