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Fatty liver in Pakistani cohort with rheumatoid arthritis
OBJECTIVE: To determine the frequency of fatty liver (non-alcoholic) disease, Framingham 10-year cardiovascular risk score in rheumatoid arthritis patients. METHODS: This study was conducted from September 1(st) to March 19, 2019, at Rheumatology OPD, Central Park Medical College Lahore. One hundred...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Professional Medical Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260920/ https://www.ncbi.nlm.nih.gov/pubmed/32494263 http://dx.doi.org/10.12669/pjms.36.4.1984 |
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author | Wagan, Abrar Ahmed Bhutoo, Abdul Qadir Khan, Daim Raheem, Abdul |
author_facet | Wagan, Abrar Ahmed Bhutoo, Abdul Qadir Khan, Daim Raheem, Abdul |
author_sort | Wagan, Abrar Ahmed |
collection | PubMed |
description | OBJECTIVE: To determine the frequency of fatty liver (non-alcoholic) disease, Framingham 10-year cardiovascular risk score in rheumatoid arthritis patients. METHODS: This study was conducted from September 1(st) to March 19, 2019, at Rheumatology OPD, Central Park Medical College Lahore. One hundred ninety two seropositive rheumatoid arthritis patients were recruited. Demographic details were noted, BP, BMI, smoking habits, and waist circumference were noted, then sent to radiology department for ultrasound scan of abdomen by an expert radiologist. On next day 10 ml blood was taken by phlebotomist for lipid profile and fasting blood sugar levels, after availability of results 10-years Framingham cardiovascular risk score was calculated. RESULTS: Females were (81.3%) mean age of (45.4) years, fatty liver was present in n=39 (20.3%). In positive cases comorbid like metabolic syndrome was present (71.8%), diabetes mellitus (33.3%), hypertension (59%) FRS score (intermediate to high in (33.3%), history of hakeem/desi medication use (51.3%), while on regression analysis all study parameters except DMARD’s had significant association with fatty liver (p<0.05). CONCLUSION: Nonalcoholic fatty liver disease is very widely prevalent in rheumatoid arthritis patients. As in general population, it is multifactorial in origin and needs careful monitoring and treatment. |
format | Online Article Text |
id | pubmed-7260920 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Professional Medical Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-72609202020-06-02 Fatty liver in Pakistani cohort with rheumatoid arthritis Wagan, Abrar Ahmed Bhutoo, Abdul Qadir Khan, Daim Raheem, Abdul Pak J Med Sci Original Article OBJECTIVE: To determine the frequency of fatty liver (non-alcoholic) disease, Framingham 10-year cardiovascular risk score in rheumatoid arthritis patients. METHODS: This study was conducted from September 1(st) to March 19, 2019, at Rheumatology OPD, Central Park Medical College Lahore. One hundred ninety two seropositive rheumatoid arthritis patients were recruited. Demographic details were noted, BP, BMI, smoking habits, and waist circumference were noted, then sent to radiology department for ultrasound scan of abdomen by an expert radiologist. On next day 10 ml blood was taken by phlebotomist for lipid profile and fasting blood sugar levels, after availability of results 10-years Framingham cardiovascular risk score was calculated. RESULTS: Females were (81.3%) mean age of (45.4) years, fatty liver was present in n=39 (20.3%). In positive cases comorbid like metabolic syndrome was present (71.8%), diabetes mellitus (33.3%), hypertension (59%) FRS score (intermediate to high in (33.3%), history of hakeem/desi medication use (51.3%), while on regression analysis all study parameters except DMARD’s had significant association with fatty liver (p<0.05). CONCLUSION: Nonalcoholic fatty liver disease is very widely prevalent in rheumatoid arthritis patients. As in general population, it is multifactorial in origin and needs careful monitoring and treatment. Professional Medical Publications 2020 /pmc/articles/PMC7260920/ /pubmed/32494263 http://dx.doi.org/10.12669/pjms.36.4.1984 Text en Copyright: © Pakistan Journal of Medical Sciences http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Wagan, Abrar Ahmed Bhutoo, Abdul Qadir Khan, Daim Raheem, Abdul Fatty liver in Pakistani cohort with rheumatoid arthritis |
title | Fatty liver in Pakistani cohort with rheumatoid arthritis |
title_full | Fatty liver in Pakistani cohort with rheumatoid arthritis |
title_fullStr | Fatty liver in Pakistani cohort with rheumatoid arthritis |
title_full_unstemmed | Fatty liver in Pakistani cohort with rheumatoid arthritis |
title_short | Fatty liver in Pakistani cohort with rheumatoid arthritis |
title_sort | fatty liver in pakistani cohort with rheumatoid arthritis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260920/ https://www.ncbi.nlm.nih.gov/pubmed/32494263 http://dx.doi.org/10.12669/pjms.36.4.1984 |
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