The endosomal lipid bis(monoacylglycero) phosphate as a potential key player in the mechanism of action of chloroquine against SARS-COV-2 and other enveloped viruses hijacking the endocytic pathway

The anti-malarial drug Chloroquine (CQ) and its derivative hydroxychloroquine have shown antiviral activities in vitro against many viruses, including coronaviruses, dengue virus and the biosafety level 4 Nipah and Hendra paramyxoviruses. The in vivo efficacy of CQ in the treatment of COVID-19 is cu...

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Detalles Bibliográficos
Autores principales: Carrière, Frédéric, Longhi, Sonia, Record, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM). 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261073/
https://www.ncbi.nlm.nih.gov/pubmed/32485205
http://dx.doi.org/10.1016/j.biochi.2020.05.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261073/
https://www.ncbi.nlm.nih.gov/pubmed/32485205
http://dx.doi.org/10.1016/j.biochi.2020.05.013

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